2-Mercaptoethyl ether

Base Information

• Chemical Name: 2-Mercaptoethyl ether
• CAS No.: 2150-02-9
• Molecular Formula: C4H10 O S2
• Molecular Weight: 138.255
• European Community (EC) Number: 218-421-5
• NSC Number: 51020,6751
• UNII: QO2W9LA7NA
• DSSTox Substance ID: DTXSID6062206
• Nikkaji Number: J208.812F
• Wikidata: Q27287386
• Mol file: 2150-02-9.mol

Synonyms:2-Mercaptoethyl ether;2150-02-9;2,2'-Oxydiethanethiol;Bis(2-mercaptoethyl) ether;Ethanethiol, 2,2'-oxybis-;68865-60-1;2,2'-Oxydi-1-ethanethiol;2,2'-Dimercaptodiethyl ether;Ethyl ether dimercaptan;2,2'-Oxybisethanethiol;2-(2-sulfanylethoxy)ethanethiol;Bis(2-mercaptoethyl)ether;.beta.-Mercaptoethyl ether;3-Oxapentane-1,5-dithiol;Ethanethiol, 2,2'-oxydi-;2,2-OXYDIETHANETHIOL;1,5-Dimercapto-3-oxapentane;2,2'-Oxybis(ethane-1-thiol);Dimercaptodiethyl ether;QO2W9LA7NA;di(2-Mercaptoethyl) ether;.beta.,.beta.'-Dimercaptodiethyl ether;NSC 6751;NSC-6751;NSC 51020;NSC-51020;Ethanethiol,2'-oxydi-;Ethanethiol,2'-oxybis-;Thiol-PEG-Thiol;2-(2-sulfanylethoxy)ethane-1-thiol;beta-Mercaptoethyl ether;di(2-mercaptoethyl)ether;UNII-QO2W9LA7NA;SCHEMBL93392;2-Mercaptoethyl ether, 95%;DTXSID6062206;NSC6751;beta,beta'-Dimercaptodiethyl ether;2-(2-mercapto-ethoxy)-ethanethiol;CAA15002;NSC51020;EINECS 218-421-5;MFCD00004889;.beta.,.beta.'-Dimercaptoethyl ether;AKOS015898454;AT13657;GS-6037;2-(2-Sulfanylethoxy)ethyl hydrosulfide #;AI3-61992;FT-0623014;O0106;J-014107;Q27287386

Chemical Property of 2-Mercaptoethyl ether

Chemical Property:

• Melting Point: −80 °C(lit.)
• Refractive Index: 1.5200-1.5240
• Boiling Point: 217 °C(lit.)
• PKA: 9.34±0.10(Predicted)
• Flash Point: 209 °F
• Density: 1.114 g/mL at 25 °C(lit.)
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 138.01730729
• Heavy Atom Count: 7
• Complexity: 28.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(2-mercaptoethyl) Ether >95.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(CS)OCCS

Technology Process of 2-Mercaptoethyl ether

There total 18 articles about 2-Mercaptoethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-oxa-1,5-dichloropentane (111-44-4) → bis(2-mercaptoethyl)ether (2150-02-9)

Guidance literature:

3-oxa-1,5-dichloropentane; With sodium trithiocarbonate; In water; at 65 ℃; for 8h;

With sulfuric acid; In water; pH=1 - 2;

DOI:10.1002/bio.1264

Reference yield: 74.0%

S,S‘-(3-oxapentane-1,5-diyl)-bis(thioacetate) (65079-30-3) → bis(2-mercaptoethyl)ether (2150-02-9)

Guidance literature:

With hydrogenchloride; In methanol; water; at 120 ℃; for 3h; Inert atmosphere;

DOI:10.3762/bjoc.12.38

Reference yield: 25.0%

polymer: monomers(s): bis(β-chloroethyl) ether; sulfur → 1,4-Oxathiane (15980-15-1) + bis(2-mercaptoethyl)ether (2150-02-9)

Guidance literature:

With sodium hydroxide; hydrazine hydrate; at 80 - 90 ℃; for 3h;

DOI:10.1023/A:1015425702523

upstream raw materials:

1,1'-oxybisethene

1,2-dichloro-ethane

3-oxa-1,5-dichloropentane

thiourea

Downstream raw materials:

1,11-diphenoxy-6-oxa-3,9-dithia-undecane

(C₆H₅)ISn(SC₂H₄)2O

(C₆H₅)(Br)Sn(SC₂H₄)2O

1,5-bis[2-(N,N-diethylacetamidooxy)thiabenzyl]-3-oxapentane

Refernces

• 1、 Jiang, Y,Huang, Zhong,Dai, Huajun,Wang, Lihua,Ying, Liu,Kou, Xingming. "A highly selective and sensitive fluorescent sensor for copper(ii) ion characterized by one dichlorofluorescein moiety and two azathia-crown ether". . p. 8292 - 8296. Retrieved 2013.
• 2、 Bedná?ová, Eva,Hybelbauerová, Simona,Jind?ich, Jind?ich. "Optimized methods for preparation of 6I-(ω-sulfanyl-alkylenesulfanyl)-β-cyclodextrin derivatives". supporting information. p. 349 - 352. Retrieved 2016/04/05.