Rifamycin PR 14

Base Information

• Chemical Name: Rifamycin PR 14
• CAS No.: 21240-38-0
• Molecular Formula: C43H54N2O12
• Molecular Weight: 790.8951
• Mol file: 21240-38-0.mol

Synonyms:Rifamycin PR 14;21240-38-0;PR 14;BRN 5402462;NCI 143-462;Rifamycin II, 3'-acetyl-1',2'-dimethyl-;[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-27-acetyl-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22,28,29-nonamethyl-6,23-dioxo-8,33-dioxa-24,29-diazapentacyclo[23.6.1.14,7.05,31.026,30]tritriaconta-1(31),2,4,9,19,21,25(32),26(30),27-nonaen-13-yl] acetate;9,4-(Epoxypentadeca(1,11,13)trienimino)-1H-benzofuro(5,4-g)indole-10,26(9H)-dione, 3-acetyl-5,6,16,18,20-pentahydroxy-14-methoxy-1,2,7,9,15,17,19,21,25-nonamethyl-, 16-acetate;LS-64145

Chemical Property of Rifamycin PR 14

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 978°Cat760mmHg
• Flash Point: 545.3°C
• Density: 1.32g/cm³
• XLogP3: 6
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 4
• Exact Mass: 790.36767516
• Heavy Atom Count: 57
• Complexity: 1620

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C5=C2C(=C(N5C)C)C(=O)C)O)C
• Isomeric SMILES: C[C@H]1/C=C/C=C(\C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C5=C2C(=C(N5C)C)C(=O)C)O)/C

Technology Process of Rifamycin PR 14

There total 1 articles about Rifamycin PR 14 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methylamino-pent-3-en-2-one (869-74-9) + Rifamycin S (13553-79-2,62623-68-1,76188-88-0,81203-58-9,101978-28-3) → 3'-Acetyl-1',2'-dimethyl-pyrrolo-<3,2-c>-4-desoxy-rifamycin SV (21240-38-0)

Guidance literature:

In methanol; for 70h; Ambient temperature;

upstream raw materials:

4-methylamino-pent-3-en-2-one

Rifamycin S

Refernces