DL-2-AMINO-5-METHYLHEX-4-ENOIC ACID

Base Information

• Chemical Name: DL-2-AMINO-5-METHYLHEX-4-ENOIC ACID
• CAS No.: 3558-31-4
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.18
• Mol file: 3558-31-4.mol

Synonyms:DL-2-AMINO-5-METHYLHEX-4-ENOIC ACID;UKRORGSYN-BB BBV-083754

Chemical Property of DL-2-AMINO-5-METHYLHEX-4-ENOIC ACID

Chemical Property:

• PSA: 63.32000
• LogP: 1.45490
• Storage Temp.: Refrigerator, Under inert atmosphere
• Solubility.: Water (Slightly, Heated, Sonicated)

Purity/Quality:

99%+, ^*data from raw suppliers

2-AMINO-5-METHYLHEX-4-ENOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Amino-5-methylhex-4-enoic Acid can be used as regulators of cell division in plant tissues.

Technology Process of DL-2-AMINO-5-METHYLHEX-4-ENOIC ACID

There total 4 articles about DL-2-AMINO-5-METHYLHEX-4-ENOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

prenyl bromide (870-63-3) → 2-amino-5-methylhex-4-enoic acid (3558-31-4)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOEt

2: aq. NaOH

With sodium hydroxide; sodium ethanolate;

DOI:10.1016/S0031-9422(00)85644-7

Reference yield:

2-amino-2-hydroxyacetic acid (4746-62-7) + 4,4,5,5-tetramethyl-2-(3-methylbut-2-enyl)-1,3,2-dioxaborolane (141550-13-2) → 2-amino-5-methylhex-4-enoic acid (3558-31-4) + 2-amino-3,3-dimethylpent-4-enoic acid

Guidance literature:

With triethylamine; In methanol; at 20 ℃; for 18h;

DOI:10.1139/v05-096

Reference yield:

Ethyl-2-acetamido-2-cyano-5-methylhex-4-enoat (19814-59-6) → 2-amino-5-methylhex-4-enoic acid (3558-31-4)

Guidance literature:

With barium dihydroxide;

DOI:10.1016/S0031-9422(00)90246-2

upstream raw materials:

Ethyl-2-acetamido-2-cyano-5-methylhex-4-enoat

2-amino-2-hydroxyacetic acid

4,4,5,5-tetramethyl-2-(3-methylbut-2-enyl)-1,3,2-dioxaborolane

prenyl bromide

Refernces

• 1、 Sugiura, Masaharu,Mori, Chieko,Hirano, Keiichi,Kobayashi, Shu. "Direct synthesis of unprotected α-amino acids via allylation of hydroxyglycine". . p. 937 - 942. Retrieved 2007/10/03.