Sucrosofate ammonium

Base Information

• Chemical Name: Sucrosofate ammonium
• CAS No.: 74135-13-0
• Molecular Formula: C₁₂H₁₄O₃₅S₈*8H₄N
• Molecular Weight: 1119.06
• UNII: 0M75U2ZH0A
• Wikidata: Q27236962
• Mol file: 74135-13-0.mol

Synonyms:Sucrosofate ammonium;74135-13-0;Sucrose Octasulfate, Ammonium Salt;UNII-0M75U2ZH0A;0M75U2ZH0A;octaazanium;[(2R,3R,4S,5R,6R)-2-[(2S,3S,4R,5R)-3,4-disulfonatooxy-2,5-bis(sulfonatooxymethyl)oxolan-2-yl]oxy-3,5-disulfonatooxy-6-(sulfonatooxymethyl)oxan-4-yl] sulfate;alpha-D-Glucopyranoside, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranosyl, tetrakis(hydrogen sulfate), octaammonium salt;Sucrose Octasulfate octaAmmonium Salt;Q27236962;.ALPHA.-D-GLUCOPYRANOSIDE, 1,3,4,6-TETRA-O-SULFO-.BETA.-D-FRUCTOFURANOSYL, TETRAKIS(HYDROGEN SULFATE), AMMONIUM SALT;.ALPHA.-D-GLUCOPYRANOSIDE, 1,3,4,6-TETRA-O-SULFO-.BETA.-D-FRUCTOFURANOSYL, TETRAKIS(HYDROGEN SULFATE), OCTAAMMONIUM SALT;131587-92-3

Chemical Property of Sucrosofate ammonium

Chemical Property:

• Melting Point: 157-159°C dec.
• PSA: 629.41000
• LogP: -0.12090
• Storage Temp.: -20°C Freezer
• Solubility.: Water (Slightly)
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 35
• Rotatable Bond Count: 13
• Exact Mass: 1117.9831246
• Heavy Atom Count: 63
• Complexity: 2130

Purity/Quality:

99% ^*data from raw suppliers

Sucrose Octasulfate, Ammonium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OC2(C(C(C(O2)COS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])COS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+]
• Isomeric SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)COS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])COS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+]
• Uses: SUCROSE OCTASULFATE, AMMONIUM SALT is used as a reference standard for the drug Sucralfate

Technology Process of Sucrosofate ammonium

There total 3 articles about Sucrosofate ammonium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Sucrose (57-50-1) → ammonium salt of sucrose octasulfate (74135-13-0,131587-92-3)

Guidance literature:

Sucrose; With sulfur trioxide pyridine complex; In pyridine; N,N-dimethyl-formamide; at 55 - 65 ℃;

With sodium hydroxide; In water; for 0.333333h; pH=6.8; activated charcoal;

With ammonium bicarbonate; In water;

Reference yield:

barium salt of sucrose octasulfate (74135-09-4) → ammonium salt of sucrose octasulfate (74135-13-0,131587-92-3)

Guidance literature:

With Amberlite IR-120 (NH₄⁽¹⁺⁾); In water;

DOI:10.1248/cpb.28.638

Reference yield:

→ ammonium salt of sucrose octasulfate (74135-13-0,131587-92-3)

Guidance literature:

upstream raw materials:

barium salt of sucrose octasulfate

Sucrose

Downstream raw materials:

sucrose octasulphate sodium salt

Refernces

• 1、 -. "Method for preparing high potency sucralfate". . . Retrieved 2008/06/13.