tert-butyl bis(4-hydroxybutyl)carbamate

Base Information

• Chemical Name: tert-butyl bis(4-hydroxybutyl)carbamate
• CAS No.: 1056441-60-1
• Molecular Formula: C13H27NO4
• Molecular Weight: 261.36
• Mol file: 1056441-60-1.mol

Synonyms:tert-butyl bis(4-hydroxybutyl)carbamate

Chemical Property of tert-butyl bis(4-hydroxybutyl)carbamate

Chemical Property:

• PSA: 70.00000
• LogP: 1.76850

Purity/Quality:

98% ^*data from raw suppliers

tert-ButylBis(4-hydroxybutyl)carbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-butyl bis(4-hydroxybutyl)carbamate

There total 3 articles about tert-butyl bis(4-hydroxybutyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + bis(5-hydroxy-butyl)amine hydrochloride (1239357-36-8) → t-butyl bis(4-hydroxybutyl)carbamate (1056441-60-1)

Guidance literature:

With triethylamine; In methanol; for 5h; Reflux;

Reference yield:

4-hydroxy-N-(4-hydroxybutyl)butanamide → t-butyl bis(4-hydroxybutyl)carbamate (1056441-60-1)

Guidance literature:

Multi-step reaction with 2 steps

1: BH₃*DMS / tetrahydrofuran / 1 h / Heating

2: Et₃N / methanol / Heating

With dimethylsulfide borane complex; triethylamine; In tetrahydrofuran; methanol;

DOI:10.1021/jo000407m

Reference yield:

4,4’-azanediylbis(butan-1-ol) (79448-06-9) + di-tert-butyl dicarbonate (24424-99-5) → t-butyl bis(4-hydroxybutyl)carbamate (1056441-60-1)

Guidance literature:

With triethylamine; In methanol; Heating;

DOI:10.1021/jo000407m

upstream raw materials:

4,4’-azanediylbis(butan-1-ol)

di-tert-butyl dicarbonate

bis(5-hydroxy-butyl)amine hydrochloride

Refernces

• 1、 -. "GERMICIDE FOR AGRICULTURE AND HORTICULTURE CONTAINING AMIDINOPYRIDINE COMPOUND". . . Retrieved 2016/10/10.