1,4-dihexylpiperazine

Base Information

• Chemical Name: 1,4-dihexylpiperazine
• CAS No.: 73073-90-2
• Molecular Formula: C₁₆H₃₄N₂
• Molecular Weight: 254.459
• Mol file: 73073-90-2.mol

Synonyms:1,4-Dihexylpiperazine

Chemical Property of 1,4-dihexylpiperazine

Chemical Property:

• Vapor Pressure: 0.000122mmHg at 25°C
• Boiling Point: 335.1°C at 760 mmHg
• Flash Point: 141.5°C
• PSA: 6.48000
• Density: 0.86g/cm³
• LogP: 3.64040

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-dihexylpiperazine

There total 3 articles about 1,4-dihexylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

piperazine (110-85-0) + 1-bromo-hexane (111-25-1) → 1,4-dihexylpiperazine (73073-90-2)

Guidance literature:

With potassium carbonate; at 100 - 110 ℃; for 1.5h; 150 deg C, 1 h;

DOI:10.1135/cccc19821130

Reference yield: 56.0%

piperazine (110-85-0) + hexan-1-ol (111-27-3) → 1,4-dihexylpiperazine (73073-90-2)

Guidance literature:

With [IrCl(Cp*)(C₁₃H₁₅N₂O₃S)]; In neat (no solvent); at 130 ℃; for 24h; Catalytic behavior; Inert atmosphere; Schlenk technique;

DOI:10.1039/c5dt02867a

Reference yield:

→ 1,4-dihexylpiperazine (73073-90-2)

Guidance literature:

1,2-Dibrom-ethan, Hexylamin, NaOH, 140 grad, 9h;

upstream raw materials:

piperazine

1-bromo-hexane

hexan-1-ol

Refernces

• 1、 Devinsky,Lacko,Mlynarcik,Krasnec. "Synthesis, IR spectra and antimicrobial activity of 1,4-dialkylpiperazine dioxides". . p. 1130 - 1138. Retrieved 2007/10/02.