DIMETHYL 2,4:3,5-DI-O-METHYLENE-D-GLUCARATE

Base Information

• Chemical Name: DIMETHYL 2,4:3,5-DI-O-METHYLENE-D-GLUCARATE
• CAS No.: 4539-77-9
• Molecular Formula: C₁₀H₁₄O₈
• Molecular Weight: 262.216
• Mol file: 4539-77-9.mol

Synonyms:DIMETHYL 2,4:3,5-DI-O-METHYLENE-D-GLUCARATE;2,4:3,5-Di-O-Methylene-D-glucaric Acid DiMethyl Ester

Chemical Property of DIMETHYL 2,4:3,5-DI-O-METHYLENE-D-GLUCARATE

Chemical Property:

• Melting Point: 106-107 °C
• Boiling Point: 321.1±42.0 °C(Predicted)
• PSA: 89.52000
• Density: 1.325±0.06 g/cm3(Predicted)
• LogP: -1.18460
• Solubility.: Chloroform, Methanol

Purity/Quality:

98% ^*data from raw suppliers

Dimethyl 2,4:3,5-Di-O-methylene-D-glucarate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Dimethyl 2,4:3,5-Di-O-methylene-D-glucarate (cas# 4539-77-9 ) is a compound useful in organic synthesis.

Technology Process of DIMETHYL 2,4:3,5-DI-O-METHYLENE-D-GLUCARATE

There total 9 articles about DIMETHYL 2,4:3,5-DI-O-METHYLENE-D-GLUCARATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O2,O4;O3,O5-dimethanediyl-D-glucaric acid (7437-68-5,7437-69-6,109007-98-9) → 2,4:3,5-Di-O-methylen-D-glucarsaeure-dimethylester (4539-77-9,7595-91-7,114006-01-8,114421-41-9)

Guidance literature:

With hydrogenchloride; methanol;

DOI:10.1021/ja01201a021 DOI:10.1039/jr9440000058

Reference yield:

2,4:3,5-dimethylene-D-gluconic acid (5323-77-3) → 2,4:3,5-Di-O-methylen-D-glucarsaeure-dimethylester (4539-77-9,7595-91-7,114006-01-8,114421-41-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous alkaline solution; potassium permanganate

2: hydrogen chloride; methanol

With hydrogenchloride; methanol; potassium permanganate; alkaline solution;

DOI:10.1021/ja01201a021

Reference yield:

D-Glucono-1,5-lactone (90-80-2,1335-57-5,4253-68-3) → 2,4:3,5-Di-O-methylen-D-glucarsaeure-dimethylester (4539-77-9,7595-91-7,114006-01-8,114421-41-9)

Guidance literature:

Multi-step reaction with 3 steps

1: concentrated aqueous hydrochloric acid

2: aqueous alkaline solution; potassium permanganate

3: hydrogen chloride; methanol

With hydrogenchloride; methanol; potassium permanganate; alkaline solution;

DOI:10.1021/ja01201a021

upstream raw materials:

O²,O⁴;O³,O⁵-dimethanediyl-D-mannaric acid

O²,O⁴;O³,O⁵-dimethanediyl-D-glucaric acid

D-Glucono-1,5-lactone

2,4:3,5-dimethylene-D-gluconic acid

Downstream raw materials:

saccharic acid 1,4-lactone

L-idaric acid

Refernces