2,4,8,10-Tetraoxaspiro[5.5]undecane

Base Information

• Chemical Name: 2,4,8,10-Tetraoxaspiro[5.5]undecane
• CAS No.: 126-54-5
• Molecular Formula: C7H12O4
• Molecular Weight: 160.17
• Hs Code.: 29125000
• European Community (EC) Number: 204-792-0
• NSC Number: 139455,49146
• UNII: ASD36945W2
• DSSTox Substance ID: DTXSID2059566
• Nikkaji Number: J43.579A
• Wikidata: Q209192
• Mol file: 126-54-5.mol

Synonyms:2,4,8,10-Tetraoxaspiro[5.5]undecane;126-54-5;Pentaerythritol diformal;Pentaerythritol bisformal;5,5'-Spirobi-m-dioxane;2,4,8,10-Tetraoxaspiro(5.5)undecane;Pentaerythritol, dimethylene-;Pentaerythritol cyclic diformal;5,5'-Spirobi-1,3-dioxane;Formaldehyde, cyclic diacetal with pentaerythritol;NSC 139455;AI3-23521;ASD36945W2;EINECS 204-792-0;Pentaerythritol, bis(cyclic acetal) with formaldehyde;NSC-139455;Pentaerythritol, bis(cyclic acetal) with formaldehyde-;2,8,10-Tetraoxaspiro[5.5]undecane;SCHEMBL577018;UNII-ASD36945W2;C123COCOC1.C2OCOC3;DTXSID2059566;NSC49146;NSC-49146;NSC139455;AKOS024319562;2,4,8,10-tetraoxaspiro[5,5]undecane;2,4,8,10-tetraoxa-spiro[5.5]undecane;FT-0631734;Q209192;N-(2-Acetoxypropyl)-N,N,O-trimethylhydroxylammonium bromide

Chemical Property of 2,4,8,10-Tetraoxaspiro[5.5]undecane

Chemical Property:

• Appearance/Colour: White crystalline mass
• Vapor Pressure: 0.0292mmHg at 25°C
• Melting Point: 48-52 °C
• Refractive Index: 1.474
• Boiling Point: 253.4 °C at 760 mmHg
• Flash Point: 108 °C
• PSA: 36.92000
• Density: 1.2 g/cm³
• LogP: -0.01860
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 160.07355886
• Heavy Atom Count: 11
• Complexity: 105

Purity/Quality:

99%, ^*data from raw suppliers

2,4,8,10-TETRAOXASPIRO[5.5]UNDECANE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2(COCO1)COCOC2

Technology Process of 2,4,8,10-Tetraoxaspiro[5.5]undecane

There total 6 articles about 2,4,8,10-Tetraoxaspiro[5.5]undecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Pentaerythritol (115-77-5) + Dimethoxymethane (109-87-5) → 5,5-bis-hydroxymethyl-[1,3]dioxane (6228-25-7) + 2,4,8,10-tetraoxaspiro[5.5]undecane (126-54-5)

Guidance literature:

Mechanism;

DOI:10.1016/S0040-4039(00)96924-7

Reference yield: 0.4%

formaldehyd (50-00-0,30525-89-4,61233-19-0) → 2,4,8,10-tetraoxaspiro[5.5]undecane (126-54-5)

Guidance literature:

With water; boric acid; at 100 ℃; for 72h; pH=3;

DOI:10.1002/jhet.348

Reference yield:

ethyl acetate (141-78-6) → 2,4,8,10-tetraoxaspiro[5.5]undecane (126-54-5)

Guidance literature:

ethyl acetate; (CH₂O)x; With sulfuric acid; at 20 ℃; for 24h;

at 80 ℃; for 7h; Further stages.;

DOI:10.1134/s1070428008020206

upstream raw materials:

formaldehyd

Pentaerythritol

Dimethoxymethane

ethyl acetate

Downstream raw materials:

tetraphenyl<4,4-bis(chloromethyl)-2,6-dioxaheptamethylene>bis-phosphonate

Refernces

• 1、 Poshkus. "An improved synthesis of 2,4,8,10-tetroxaspiro[5.5]undecane (Pentaerythritol diformal)". . p. 1075 - 1076. Retrieved 1979.
• 2、 Maheen, Gull,Tian, Ge,Song, Zhiguang,He, Chao,Shi, Zhan,Liu, Ziwei,Yuan, Hongming,Feng, Shouhua. "A novel synthetic route to synthesize 2,4,8, 10-tetraoxaspiro[5.5]-undecane from formaldehyde under hydrothermal conditions". . p. 483 - 485. Retrieved 2010.