Diphenyl(pentafluorophenyl)phosphine

Base Information

• Chemical Name: Diphenyl(pentafluorophenyl)phosphine
• CAS No.: 5525-95-1
• Molecular Formula: C18H10F5P
• Molecular Weight: 352.243
• Hs Code.: 29310099
• European Community (EC) Number: 633-503-4
• NSC Number: 175502
• DSSTox Substance ID: DTXSID10306323
• Nikkaji Number: J46.728F
• Wikidata: Q82053364
• Mol file: 5525-95-1.mol

Synonyms:Diphenyl(pentafluorophenyl)phosphine;5525-95-1;(Pentafluorophenyl)diphenylphosphine;(Perfluorophenyl)diphenylphosphine;(2,3,4,5,6-pentafluorophenyl)-diphenylphosphane;Phosphine, (pentafluorophenyl)diphenyl-;C18H10F5P;NSC175502;Pentafluorodiphenylphosphine;SCHEMBL588775;Diphenylpentafluorophenyphosphine;DTXSID10306323;KUTXTUCJQJPJBH-UHFFFAOYSA-N;(Pentafluorophhenyl)diphenylphosphine;MFCD00000290;AKOS007930399;NSC-175502;PENTAFLUOROPHENYLDIPHENYLPHOSPHINE;CS-0085775;FT-0625245;P1176;T72607;A830558;(2,3,4,5,6-Pentafluorophenyl)(diphenyl)phosphine

Chemical Property of Diphenyl(pentafluorophenyl)phosphine

Chemical Property:

• Appearance/Colour: white to light yellow crystal powder
• Vapor Pressure: 7.18E-05mmHg at 25°C
• Melting Point: 71-72 °C(lit.)
• Boiling Point: 353.7 °C at 760 mmHg
• Flash Point: 167.7 °C
• PSA: 13.59000
• LogP: 4.14030
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: soluble in Chloroform
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 352.04402813
• Heavy Atom Count: 24
• Complexity: 363

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diphenyl(pentafluorophenyl)phosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=C(C(=C(C(=C3F)F)F)F)F
• Uses: The reaction of (pentafluorophenyl)diphenylphosphine with C-ethoxycarbonyl-(p-methoxyphenyl) nitrile imine was used to synthesize [2,3,4,5-tetrafluoro-6-(p- methoxyphenylamino)phenyl]diphenylphosphine oxide whose reduction with trichlorosilane. the reactions of (pentafluorophenyl)diphenylphosphine and bis(penta- fluorophenyl)(phenyl)phosphine with nitrilimines (Housgen 1,3-dipoles) involves two-stage cycloaddi- tion and leads to formation of sufficiently stable fluorophosphoranes.

Technology Process of Diphenyl(pentafluorophenyl)phosphine

There total 5 articles about Diphenyl(pentafluorophenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

Hexafluorobenzene (392-56-3) + triphenylphosphine (603-35-0) → (pentafluorophenyl)diphenylphosphine (5525-95-1)

Guidance literature:

triphenylphosphine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

Hexafluorobenzene; In tetrahydrofuran; for 0.166667h; Inert atmosphere;

DOI:10.1021/ol900222v

Reference yield: 56.0%

trimethyl(pentafluorophenyl)silane (1206-46-8) + diphenylcyanophosphine (4791-48-4) → (pentafluorophenyl)diphenylphosphine (5525-95-1)

Guidance literature:

With (K-18-crown-6 ether) cyanide; In acetonitrile; at -45 - 20 ℃; for 3h;

DOI:10.1016/S0022-1139(01)00513-9

Reference yield: 37.5%

bromopentafluorobenzene (344-04-7) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → (pentafluorophenyl)diphenylphosphine (5525-95-1)

Guidance literature:

bromopentafluorobenzene; With magnesium; In tetrahydrofuran; for 0.666667h; Heating;

chloro-diphenylphosphine; In tetrahydrofuran;

DOI:10.1139/v01-075

upstream raw materials:

trimethyl(pentafluorophenyl)silane

diphenylcyanophosphine

bromopentafluorobenzene

chloro-diphenylphosphine

Downstream raw materials:

Rh₂(OOCCH₃)2[(C₆H₄)P(C₆H₅)(C₆F₅)]2(H₂O)2

Rh₂(OOCCH₃)2[(C₆H₄)P(C₆H₅)(C₆F₅)]2(H₂O)2

Rh₂(OOCCH₃)2[(C₆H₄)P(C₆H₅)(C₆F₅)]2(H₂O)2

(η(5)-C5Me4H)RhCl2(PPh2(C6F5))

Refernces

• 1、 Panne, Patricia,Naumann, Dieter,Hoge, Berthold. "Cyanide initiated perfluoroorganylations with perfluoroorgano silicon compounds". . p. 283 - 286. Retrieved 2007/10/03.