Benzoyl(2-methylpyridinium-1-yl)amine anion

Base Information

• Chemical Name: Benzoyl(2-methylpyridinium-1-yl)amine anion
• CAS No.: 17408-47-8
• Molecular Formula: C13H12N2O
• Molecular Weight: 212.251
• Mol file: 17408-47-8.mol

Synonyms:Benzoyl(2-methylpyridinio)amine anion;Benzoyl(2-methylpyridinium-1-yl)amine anion;hydroxide inner salt

Chemical Property of Benzoyl(2-methylpyridinium-1-yl)amine anion

Chemical Property:

• Melting Point: 111 °C
• PSA: 37.82000
• LogP: 2.94970

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoyl(2-methylpyridinium-1-yl)amine anion

There total 6 articles about Benzoyl(2-methylpyridinium-1-yl)amine anion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

α-picoline (109-06-8) + benzoyl chloride (98-88-4) → 2-methyl-N-(benzoylimino)pyridinium ylide (17408-47-8)

Guidance literature:

α-picoline; With O-(2,4-dinitrophenyl)hydroxylamine; In tetrahydrofuran; water; at 40 ℃; for 12h;

benzoyl chloride; With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1021/ja0525298

Reference yield:

1-amino-2-methyl-pyridinium 2,4-dinitro-phenolate (56150-02-8) + benzoyl chloride (98-88-4) → 2-methyl-N-(benzoylimino)pyridinium ylide (17408-47-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 4h;

DOI:10.1021/jo034456l

Reference yield:

benzoyl chloride (98-88-4) + 2-methylpyridine N-imine (51135-75-2) → 2-methyl-N-(benzoylimino)pyridinium ylide (17408-47-8)

Guidance literature:

With sodium hydroxide; at 25 ℃; for 12h; Yield given;

DOI:10.1021/jm00384a018

upstream raw materials:

α-picoline

benzoyl chloride

2-methylpyridine N-imine

1-amino-2-methyl-pyridinium 2,4-dinitro-phenolate

Downstream raw materials:

C₁₉H₁₆N₂O

C₁₉H₁₆N₂O

benzoyl(2-methyl-6-neopentylpyridinium-1-yl)azanide

2-phenylpyrazolo[1,5-a]pyridin-3-yl acetate

Refernces

• 1、 Mousseau, James J.,Bull, James A.,Ladd, Carolyn L.,Fortier, Angelique,Sustac Roman, Daniela,Charette, Andre B.. "Synthesis of 2- and 2,3-substituted Pyrazolo[1,5- a ]pyridines: Scope and mechanistic considerations of a domino direct alkynylation and cyclization of n -iminopyridinium ylides using alkenyl bromides, alkenyl iodides, and alkynes". experimental part. p. 8243 - 8261. Retrieved 2012/01/03.
• 2、 Legault, Claude,Charette, Andre B.. "Complexation promoted additions to N-benzoyliminopyridinium ylides. A novel and highly regioselective approach to polysubstituted piperidines". . p. 6360 - 6361. Retrieved 2007/10/03.