CONCANAVALIN A TYPE III

Base Information

• Chemical Name: CONCANAVALIN A TYPE III
• CAS No.: 11028-71-0
• Molecular Formula: Unspecified
• Molecular Weight: 0
• Hs Code.: 35040090
• Mol file: 11028-71-0.mol

Synonyms:Con A;Concanavaline A;Lectins, concanavalins A;

Chemical Property of CONCANAVALIN A TYPE III

Chemical Property:

• Flash Point: 39 °C
• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: 2-8°C
• Solubility.: PBS: 5 mg/mL, slightly hazy
• Water Solubility.: Slightly soluble in water and phosfate buffered saline.

Purity/Quality:

98%,99%, ^*data from raw suppliers

Concanavalin A ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 10-42/43-63-40-20/21/22
• Safety Statements: 36-24/25-45-36/37-23-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Concanavalin A is a unique lectin purified from the jack bean, C. ensiformis, that selectively cross-links cell-surface glycoproteins and affects the initiation of cell agglutination, mitogenesis, and apoptosis. Concanavalin A specifically binds to α-mannose and α-galactose structures found in sugars, glycoproteins, and glycolipids and has been used in affinity chromatography purifications of various glycoproteins and cellular structures. At 20 mg/kg concanavalin A is also used to induce liver injury in experimental mouse models of autoimmune hepatitis in order to study immune regulation by macrophages and T cells. Concanavalin A is toxic to several tumor cell lines and has been reported to induce programmed cell death of cortical neurons by a mechanism similar to that of the amyloid β peptide. As a reagent in analytical and preparative biochemistry; as a probe in studies of cell surface membrane dynamics and cell division. Concanavalin A is a plant lectin that is a T-cell mitogen, and induces apoptosis in human fibroblasts.