4-(3-Morpholinopropoxy)phenylboronic acid

Base Information

• Chemical Name: 4-(3-Morpholinopropoxy)phenylboronic acid
• CAS No.: 1003028-41-8
• Molecular Formula: C13H20BNO4
• Molecular Weight: 265.1132
• Mol file: 1003028-41-8.mol

Synonyms:4-(3-Morpholinopropoxy)phenylboronic acid

Chemical Property of 4-(3-Morpholinopropoxy)phenylboronic acid

Chemical Property:

• PSA: 62.16000
• LogP: -0.59460

Purity/Quality:

＞95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(3-Morpholinopropoxy)phenylboronic acid

There total 1 articles about 4-(3-Morpholinopropoxy)phenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-bromo-4-(3-morpholin-4-yl-propoxy)benzene → 4-(3-morpholin-4-yl-propoxy)phenylboronic acid (1003028-41-8)

Guidance literature:

1-bromo-4-(3-morpholin-4-yl-propoxy)benzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.75h;

With Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃;

With ammonium chloride; In tetrahydrofuran; hexane; Further stages.;

DOI:10.1016/j.tet.2007.10.045

Reference yield: 57.0%

10-acetyl-2,7-dibromo-indolo[3,2-b]quinoline (706780-98-5) + 4-(3-morpholin-4-yl-propoxy)phenylboronic acid (1003028-41-8) → 2,7-bis[4'-(3''-morpholin-4''-yl-propoxy)phenyl]-10H-indolo[3,2-b]quinoline

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; for 18h; Heating;

DOI:10.1016/j.tet.2007.10.045

Reference yield:

4-(3-morpholin-4-yl-propoxy)phenylboronic acid (1003028-41-8) + 2-bromo-5-(3-morpholin-4-yl-propoxy)-benzoic acid methyl ester → 4,4'-bis-(3-morpholin-4-yl-propoxy)-biphenyl-2-carboxylic acid methyl ester

Guidance literature:

With sodium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 85 ℃;

DOI:10.1016/j.bmc.2004.07.002

Refernces