Diclomezine

Base Information

• Chemical Name: Diclomezine
• CAS No.: 62865-36-5
• Deprecated CAS: 1135442-72-6
• Molecular Formula: C11H8 Cl2 N2 O
• Molecular Weight: 255.103
• Hs Code.: 2933990013
• European Community (EC) Number: 613-092-8
• UNII: UNB23N8AVX
• DSSTox Substance ID: DTXSID0058146
• Nikkaji Number: J27.903J
• Wikidata: Q19278175
• Mol file: 62865-36-5.mol

Synonyms:Diclomezine;62865-36-5;Monguard;Diclomezine [ISO];6-(3,5-Dichloro-4-methylphenyl)-3(2H)-pyridazinone;3-(3,5-dichloro-4-methylphenyl)-1H-pyridazin-6-one;UNII-UNB23N8AVX;UNB23N8AVX;SF-7531;BRN 0884391;F-850;6-(3,5-dichloro-4-methylphenyl)pyridazin-3(2H)-one;Diclomezine 100 microg/mL in Acetone;3(2H)-Pyridazinone, 6-(3,5-dichloro-4-methylphenyl)-;6-(3,5-dichloro-4-methylphenyl)-3-pyridazone;6-(3,5-dichloro-p-tolyl)pyridazin-3(2H)-one;SCHEMBL21550;DTXSID0058146;CHEBI:81759;LS-129851;FT-0756546;C18458;Diclomezine, PESTANAL(R), analytical standard;6-(3,5-dichloro-4-methylphenyl)-3(2H)pyridazinone;Q19278175

Chemical Property of Diclomezine

Chemical Property:

• Melting Point: 248～255℃
• Refractive Index: 1.643
• PSA: 45.75000
• Density: 1.44 g/cm³
• LogP: 3.05210
• Storage Temp.: 0-6°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 254.0013683
• Heavy Atom Count: 16
• Complexity: 342

Purity/Quality:

98%Min ^*data from raw suppliers

Diclomezin ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 23
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1Cl)C2=NNC(=O)C=C2)Cl
• Uses: Diclomezin is a fungicide used in pesticide formulations.

Technology Process of Diclomezine

There total 6 articles about Diclomezine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

6-(3,5-dichloro-4-methylphenyl)-4-methylthio-4,5-dihydro-3(2H)-pyridazinone → diclomezin (62865-36-5)

Guidance literature:

With hydrogenchloride; In sodium hydroxide;

Reference yield: 86.2%

methyl 4-(3,5-dichloro-4-methylphenyl)-2-methoxy-4-oxobutyrate → diclomezin (62865-36-5)

Guidance literature:

With hydrazine hydrate; acetic acid; In water;

Reference yield: 76.5%

4-(3,5-dichloro-4-methylphenyl)-4-oxo-2-butenoic acid + sodium thiomethoxide (5188-07-8) → diclomezin (62865-36-5)

Guidance literature:

With hydrogenchloride; hydrazine hydrate; In water;

upstream raw materials:

sodium thiomethoxide

6-(3,5-dichloro-4-methyl-phenyl)-4,5-dihydro-2H-pyridazin-3-one

Downstream raw materials:

6-(3,5-Dichloro-4-methylphenyl)-3-N,N-dimethylcarbamoyloxypyridazine

2-butoxycarbonyl-6-(3,5-dichloro-4-methylphenyl)-3-pyridazone

6-(3,5-dichloro-4-methylphenyl)-2-methoxycarbonyl-3-pyridazone

6-(3,5-Dichloro-4-methylphenyl)-3(2H)pyridazinethione

Refernces

• 1、 -. "Process for producing antifungal oyridazinone derivatives". . . Retrieved 2008/06/13.