1-cyanocyclobutanecarboxylic acid

Base Information

• Chemical Name: 1-cyanocyclobutanecarboxylic acid
• CAS No.: 30491-91-9
• Molecular Formula: C6H7NO2
• Molecular Weight: 125.127
• Hs Code.: 2926909090
• Mol file: 30491-91-9.mol

Synonyms:1-cyanocyclobutanecarboxylic acid

Chemical Property of 1-cyanocyclobutanecarboxylic acid

Chemical Property:

• Vapor Pressure: 5.01E-05mmHg at 25°C
• Melting Point: 68-69°
• Boiling Point: 324.3°C at 760 mmHg
• PKA: 2.41±0.20(Predicted)
• Flash Point: 150°C
• PSA: 61.09000
• Density: 1.27g/cm³
• LogP: 0.76488
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Cyanocyclobutanecarboxylicacid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-36-52
• Safety Statements: 26-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-cyanocyclobutanecarboxylic acid

There total 3 articles about 1-cyanocyclobutanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 1-cyano-1-cyclobutanecarboxylate (28246-87-9) → 1-cyanocyclobutane-1-carboxylic acid (30491-91-9)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja00730a021

Reference yield:

ethyl 2-cyanoacetate (105-56-6) + 1,3-dibromo-propane (109-64-8) → 1-cyanocyclobutane-1-carboxylic acid (30491-91-9)

Guidance literature:

With sodium ethanolate; man verseift den Aethylester mit methylalkoh. Kali;

Reference yield:

→ 1-cyanocyclobutane-1-carboxylic acid (30491-91-9)

Guidance literature:

entspr. Ester (5B), alk. Hydrolyse;

upstream raw materials:

ethyl 2-cyanoacetate

1,3-dibromo-propane

ethyl 1-cyano-1-cyclobutanecarboxylate

Downstream raw materials:

carbon dioxide

cyclobutanecarbonitrile

cyclobutane-1,1'-dicarboxylic acid

Refernces