L-Ornithine, N5-[iMino(nitroaMino)Methyl]-, ethyl ester, hydrochloride

Base Information

• Chemical Name: L-Ornithine, N5-[iMino(nitroaMino)Methyl]-, ethyl ester, hydrochloride
• CAS No.: 37682-82-9
• Molecular Formula: C8H18ClN5O4
• Molecular Weight: 283.715
• Mol file: 37682-82-9.mol

Synonyms:L-Ornithine, N5-[iMino(nitroaMino)Methyl]-, ethyl ester, hydrochloride

Chemical Property of L-Ornithine, N5-[iMino(nitroaMino)Methyl]-, ethyl ester, hydrochloride

Chemical Property:

• PSA: 146.05000
• LogP: 1.86970

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Ornithine, N5-[iMino(nitroaMino)Methyl]-, ethyl ester, hydrochloride

There total 1 articles about L-Ornithine, N5-[iMino(nitroaMino)Methyl]-, ethyl ester, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethanol (64-17-5) + N-nitro-L-arginine (2149-70-4,13855-78-2,38733-00-5) → Nω-nitro-L-arginine ethyl ester; hydrochloride (37682-82-9)

Guidance literature:

With hydrogenchloride; for 0.25h; Heating;

DOI:10.1016/j.ejmech.2004.02.012

Reference yield:

Nω-nitro-L-arginine ethyl ester; hydrochloride (37682-82-9) + N-(Benzyloxycarbonyl)glycine (1138-80-3) → Nα-(N-benzyloxycarbonyl-glycyl)-Nω-nitro-L-arginine ethyl ester (109067-83-6) + acetonitrile (75-05-8,26809-02-9)

Guidance literature:

With tetrahydrofuran; triethylamine; dicyclohexyl-carbodiimide;

Reference yield:

Nω-nitro-L-arginine ethyl ester; hydrochloride (37682-82-9) + N-(Benzyloxycarbonyl)glycine (1138-80-3) → dichloromethane (75-09-2) + Nα-(N-benzyloxycarbonyl-glycyl)-Nω-nitro-L-arginine ethyl ester (109067-83-6)

Guidance literature:

With tetrahydrofuran; triethylamine; dicyclohexyl-carbodiimide;

upstream raw materials:

ethanol

N-nitro-L-arginine

Downstream raw materials:

dichloromethane

N^α-(N-benzyloxycarbonyl-glycyl)-N^ω-nitro-L-arginine ethyl ester

acetonitrile

Refernces