N-(3-(benzyloxy)-4-Methoxyphenethyl)acetaMide

Base Information Edit

Chemical Name:N-(3-(benzyloxy)-4-Methoxyphenethyl)acetaMide
CAS No.:55161-43-8
Molecular Formula:C18H21NO3
Molecular Weight:299.37
Hs Code.:
Mol file:55161-43-8.mol

Synonyms:N-(3-(benzyloxy)-4-Methoxyphenethyl)acetaMide;N-[2-[4-methoxy-3-(phenylmethoxy)phenyl]ethyl]acetamide

Suppliers and Price of N-(3-(benzyloxy)-4-Methoxyphenethyl)acetaMide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of N-(3-(benzyloxy)-4-Methoxyphenethyl)acetaMide Edit

Chemical Property:

Melting Point:122-123 °C
Boiling Point:505.5±45.0 °C(Predicted)
PKA:16.16±0.46(Predicted)
PSA：47.56000
Density:1.109±0.06 g/cm3(Predicted)
LogP:3.34370

Purity/Quality:: >96% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(3-(benzyloxy)-4-Methoxyphenethyl)acetaMide

There total 13 articles about N-(3-(benzyloxy)-4-Methoxyphenethyl)acetaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 36455-21-7
3-benzyloxy-4-methoxyphenylethylamine

: 108-24-7
acetic anhydride

: 55161-43-8
N-{2-[3-(benzyloxy)-4-methoxyphenyl]ethyl}acetamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;
DOI:10.1002/cmdc.201300261

Reference yield:

: 6346-05-0
3-benzyloxy-4-methoxybenzaldehyde

: 55161-43-8
N-{2-[3-(benzyloxy)-4-methoxyphenyl]ethyl}acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / NH₄OAc; AcOH / 4 h / Heating

2: 63 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 2 h / Heating

3: 5percent aq. NaOH / CH₂Cl₂ / 2 h / 20 °C

With lithium aluminium tetrahydride; ammonium acetate; acetic acid; In tetrahydrofuran; diethyl ether; dichloromethane; 3: Schotten-Baumann reaction;
DOI:10.1021/jm020831a