[3,5-Di(hydroxyimino)piperazino]phenyl ketone

Base Information

• Chemical Name: [3,5-Di(hydroxyimino)piperazino]phenyl ketone
• CAS No.: 36064-37-6
• Molecular Formula: C₁₁H₁₂N₄O₃
• Molecular Weight: 248.241
• Hs Code.: 2933599090
• Mol file: 36064-37-6.mol

Synonyms:[3,5-Di(hydroxyimino)piperazino]phenyl ketone;4-Benzoyl-2,6-piperazinedione dioxime

Chemical Property of [3,5-Di(hydroxyimino)piperazino]phenyl ketone

Chemical Property:

• PSA: 97.52000
• LogP: 0.57410

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [3,5-Di(hydroxyimino)piperazino]phenyl ketone

There total 3 articles about [3,5-Di(hydroxyimino)piperazino]phenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-bis(cyanomethyl)benzamide (36130-48-0) → 4-Benzoyl-piperazine-2,6-dione dioxime (36064-37-6)

Guidance literature:

With hydroxylamine hydrochloride; potassium carbonate; In methanol; water; for 2h; Heating;

Reference yield:

benzoyl chloride (98-88-4) → 4-Benzoyl-piperazine-2,6-dione dioxime (36064-37-6)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / H₂O; CH₂Cl₂ / 2 h / Ambient temperature

2: NH₂OH*HCl, K₂CO₃ / H₂O; methanol / 2 h / Heating

With hydroxylamine hydrochloride; potassium carbonate; In methanol; dichloromethane; water;

Reference yield:

→ 4-benzoyl-piperazine-2,6-dione dioxime (36064-37-6)

Guidance literature:

N-Benzoyliminodiacetonitril , Hydroxylamin;

DOI:10.1039/P19720001009

upstream raw materials:

N,N-bis(cyanomethyl)benzamide

benzoyl chloride

Downstream raw materials:

4-benzoylpiperazine-2,6-dione

Refernces