5alpha-Androstane-11,17-dione, 3beta-hydroxy-

Base Information

• Chemical Name: 5alpha-Androstane-11,17-dione, 3beta-hydroxy-
• CAS No.: 7090-90-6
• Molecular Formula: C₁₉H₂₈O₃
• Molecular Weight: 304.43
• DSSTox Substance ID: DTXSID601024473
• Nikkaji Number: J104.140A
• Mol file: 7090-90-6.mol

Synonyms:7090-90-6;11-Ketoepiandrosterone;3-Hydroxyandrostane-11,17-dione #;5.alpha.-Androstane-11,17-dione, 3.beta.-hydroxy-;SCHEMBL22446755;IUNYGQONJQTULL-LMCNQGNMSA-N;Androstane-11,17-dione, 3-hydroxy-, (3.beta.,5.alpha.)-;DTXSID601024473;5alpha-Androstan-3beta-ol-11,17-dione;5.alpha.-Androstan-3.beta.-ol-11,17-dione;(3beta,5alpha)-3-Hydroxyandrostane-11,17-dione;3.beta.-Hydroxy-5.alpha.-androstane-11,17-dione

Chemical Property of 5alpha-Androstane-11,17-dione, 3beta-hydroxy-

Chemical Property:

• PSA: 54.37000
• LogP: 3.13810
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 304.20384475
• Heavy Atom Count: 22
• Complexity: 527

Purity/Quality:

95%-98% ^*data from raw suppliers

11-KETOISOANDROSTERONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC12CCC(CC1CCC3C2C(=O)CC4(C3CCC4=O)C)O
• Isomeric SMILES: C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CCC4=O)C)O

Technology Process of 5alpha-Androstane-11,17-dione, 3beta-hydroxy-

There total 10 articles about 5alpha-Androstane-11,17-dione, 3beta-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3α-hydroxy-5β-androstane-11,17-dione (739-27-5,1231-82-9,7090-90-6,28336-28-9,40272-95-5,94991-82-9,109838-19-9)

Guidance literature:

With platinum; Hydrogenation_.und anschliessenden Behandeln mit Blei(IV)-acetat;

DOI:10.1021/ja01098a004

Reference yield:

→ 3α-hydroxy-5β-androstane-11,17-dione (739-27-5,1231-82-9,7090-90-6,28336-28-9,40272-95-5,94991-82-9,109838-19-9)

Guidance literature:

With sodium bismuthate;

Reference yield:

3α-hydroxy-5β-pregnane-11,20-dione (565-99-1) → 3α-hydroxy-5β-androstane-11,17-dione (739-27-5,1231-82-9,7090-90-6,28336-28-9,40272-95-5,94991-82-9,109838-19-9)

Guidance literature:

With ethyl nitrite; ethanol; sodium ethanolate; Behandeln des Reaktionsprodukts mit wss.HCl;

upstream raw materials:

3α-hydroxy-5β-pregnane-11,20-dione

Downstream raw materials:

5α-androstane-3,11,17-trione

3β-(toluene-4-sulfonyloxy)-5α-androstane-11,17-dione

(3α,5α)-3-hydroxyandrostane-11,17-dione

5α-androst-2-ene-11,17-dione

Refernces