Tetrahydropalmatine hydrochloride

Base Information

• Chemical Name: Tetrahydropalmatine hydrochloride
• CAS No.: 2506-20-9
• Molecular Formula: C₂₁H₂₅NO₄*ClH
• Molecular Weight: 391.895
• NSC Number: 209411,132058,132057
• UNII: 4AA8F911N9
• Wikidata: Q27259340
• ChEMBL ID: CHEMBL1412574
• Mol file: 2506-20-9.mol

Synonyms:Tetrahydropalmatine hydrochloride;6024-85-7;Tetrahydropalmatine HCl;Tetrahydropalmatine (hydrochloride);dl-Tetrahydropalmatine hydrochloride;2506-20-9;DL-Tetrahydropalmatine (hydrochloride);NSC-132057;NSC-209411;(+/-)-tetrahydropalmatine hydrochloride;2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline;hydrochloride;2,3,9,10-Tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[3,2-a]isoquinoline hydrochloride;Tetrahydropalmatine hydrochloride, (+/-)-;2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline hydrochloride;SMR000008833;4AA8F911N9;WLN: T D6 B666 KN&TT&J GO1 HO1 PO1 QO1 &GH;D-Tetrahydropalmatine hydrochloride;MLS000029596;O(C)c1cc2c(CCN3Cc4c(ccc(OC)c4OC)CC23)cc1OC;NSC-132058;Berbine, 2,3,9,10-tetramethoxy-, hydrochloride, (.+.)-;6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, hydrochloride, (.+.)-;MLS002535962;SCHEMBL3502167;CHEMBL1412574;HY-N0300A;Palmatine, hydrochloride, (+)-;EX-A6787;NSC132057;NSC132058;NSC209411;s3854;Palmatine, hydrochloride, (.+-.)-;TETRAHYDROPALMATINE HCL [INCI];AKOS024399264;AC-8031;CCG-268548;(D,L)-Tetrahydropalmatine hydrochloride;CS-0018322;FT-0698667;Berbine,3,9,10-tetramethoxy-, hydrochloride;C16053;A832652;Berbine,3,9,10-tetramethoxy-, hydrochloride, (+)-;Q27259340;TETRAHYDROPALMATINE DL-FORM HYDROCHLORIDE [MI];13a.beta.-Berbine,3,9,10-tetramethoxy-, hydrochloride;Berbine,3,9,10-tetramethoxy-, hydrochloride, (.+-.)-;BERBINE, 2,3,9,10-TETRAMETHOXY-, HYDROCHLORIDE, (+/-)-;6H-Dibenzo[a, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, hydrochloride;6H-Dibenzo[a, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, hydrochloride, (.+-.)-;6H-Dibenzo[a, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, hydrochloride, (R)-;2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline hydrochloride;6H-DIBENZO(A,G)QUINOLIZINE, 5,8,13,13A-TETRAHYDRO-2,3,9,10-TETRAMETHOXY-, HYDROCHLORIDE (1:1)

Chemical Property of Tetrahydropalmatine hydrochloride

Chemical Property:

• PSA: 40.16000
• LogP: 4.11640
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 391.1550360
• Heavy Atom Count: 27
• Complexity: 475

Purity/Quality:

99% ^*data from raw suppliers

L-Tetrahydropalmatine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC.Cl

Technology Process of Tetrahydropalmatine hydrochloride

There total 1 articles about Tetrahydropalmatine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetrahydropalmatine (483-14-7,2934-97-6,3520-14-7,10097-84-4,84-38-8) → 2,3,9,10-tetramethoxy-13aα-berbine; hydrochloride (2506-20-9,4880-82-4,6024-83-5,6024-85-7)

Guidance literature:

With hydrogenchloride; In methanol; water;

DOI:10.1055/s-0031-1280126

upstream raw materials:

tetrahydropalmatine

Refernces