4-BENZYLOXY-3-ETHOXYBENZALDEHYDE

Base Information

• Chemical Name: 4-BENZYLOXY-3-ETHOXYBENZALDEHYDE
• CAS No.: 60186-33-6
• Molecular Formula: C16H16O3
• Molecular Weight: 256.301
• Mol file: 60186-33-6.mol

Synonyms:4-Benzyloxy-3-ethoxybenzaldehyde;

Chemical Property of 4-BENZYLOXY-3-ETHOXYBENZALDEHYDE

Chemical Property:

• Vapor Pressure: 8.99E-07mmHg at 25°C
• Melting Point: 56-58°C
• Refractive Index: 1.581
• Boiling Point: 405.1 °C at 760 mmHg
• Flash Point: 190.4 °C
• PSA: 35.53000
• Density: 1.132 g/cm³
• LogP: 3.47680
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

4-(Benzyloxy)-3-ethoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BENZYLOXY-3-ETHOXYBENZALDEHYDE

There total 3 articles about 4-BENZYLOXY-3-ETHOXYBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-hydroxy-3-ethoxybenzaldehyde (121-32-4) + benzyl bromide (100-39-0) → 3-ethoxy-4-benzyloxybenzaldehyde (60186-33-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 40 ℃; for 2h;

DOI:10.1016/j.bmcl.2015.09.010

Reference yield:

4-hydroxy-3-ethoxybenzaldehyde (121-32-4) + benzyl chloride (100-44-7) → 3-ethoxy-4-benzyloxybenzaldehyde (60186-33-6)

Guidance literature:

With sodium ethanolate; potassium iodide;

Reference yield:

ethyl iodide (75-03-6) → 3-ethoxy-4-benzyloxybenzaldehyde (60186-33-6)

Guidance literature:

With potassium carbonate;

upstream raw materials:

4-hydroxy-3-ethoxybenzaldehyde

benzyl chloride

ethyl iodide

benzyl bromide

Downstream raw materials:

(E)-ethyl 3-{3-ethoxy-4-(benzyloxy)phenyl}acrylate

Refernces

• 1、 -. "NEW PHARMACEUTICAL COMPOUNDS". Page/Page column 28-29. . Retrieved 2008/06/13.
• 2、 -. "AMIDE COMPOUND AND METHOD OF CONTROLLING PLANT DISEASE WITH THE SAME". Page/Page column 95. . Retrieved 2010/02/14.