gypsogenin-3-O-glucuronide

Base Information

• Chemical Name: gypsogenin-3-O-glucuronide
• CAS No.: 96553-02-5
• Molecular Formula: C37H56O10
• Molecular Weight: 660.846
• Hs Code.: 29389090
• Mol file: 96553-02-5.mol

Synonyms:Methyl(gypsogenin-3-O-β-D-gluco pyranoside)uronate;gypsogenin-3-O-β-D-glucopyranosideuronate;(3beta,4alpha)-17-Carboxy-23-oxo-28-norolean-12-en-3-yl-beta-D-glucopyranosiduronic acid 6-methyl ester;Methyl gypsogenin 3-O-beta-D-glucuronopyranoside;Gypsogenin3-O-β-D-glucuronide 6'-methyl ester

Chemical Property of gypsogenin-3-O-glucuronide

Chemical Property:

• Boiling Point: 743.1±60.0 °C(Predicted)
• PKA: 4.62±0.70(Predicted)
• PSA: 159.82000
• Density: 1.27±0.1 g/cm3(Predicted)
• LogP: 4.41750

Purity/Quality:

98%,99%, ^*data from raw suppliers

Gypsogenin-3-O-glucuronide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of gypsogenin-3-O-glucuronide

There total 2 articles about gypsogenin-3-O-glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C49H76O19 (96552-97-5) → gypsogenin (639-14-5) + (2S,3S,4S,5R,6R)-6-((3S,4S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-Carboxy-4-formyl-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yloxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester (96553-02-5) + methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranoside (28251-53-8) + methyl 2,3,4-tri-O-acetyl-β-L-rhamnopyranoside (31085-67-3)

Guidance literature:

With hydrogenchloride; In methanol; for 0.5h; Further byproducts given; Heating;

DOI:10.1248/cpb.33.464

Reference yield:

C49H76O20 (96552-98-6) → quillaic acid (631-01-6) + (2S,3S,4S,5R,6R)-6-((3S,4S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-Carboxy-4-formyl-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yloxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester (96553-02-5) + methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranoside (28251-53-8) + methyl 2,3,4-tri-O-acetyl-β-L-rhamnopyranoside (31085-67-3)

Guidance literature:

With hydrogenchloride; In methanol; for 0.5h; Further byproducts given; Heating;

DOI:10.1248/cpb.33.464

Reference yield: 36.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + methyl (28-Hydroxy-23,28-dioxoolean-12-en-3β-yl β-D-Glucopyranoside)uronate (96553-02-5) → methyl β-D-glucuronopyranoside methyl ester (18486-38-9,528584-66-9) + (2S,3S,4S,5R,6R)-6-((3S,4S,4aR,6aR,6bS,8aS,14bR)-4-Formyl-8a-methoxycarbonyl-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yloxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester (111869-97-7) + C32H50O4 (97892-78-9) + 1-O-methyl-α-D-glucopyranuronic acid methyl ester (18486-51-6,528584-66-9)

Guidance literature:

In methanol; diethyl ether;

upstream raw materials:

C₄₉H₇₆O₁₉

C₄₉H₇₆O₂₀

Downstream raw materials:

methyl β-D-glucuronopyranoside methyl ester

(2S,3S,4S,5R,6R)-6-((3S,4S,4aR,6aR,6bS,8aS,14bR)-4-Formyl-8a-methoxycarbonyl-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yloxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester

C₃₂H₅₀O₄

1-O-methyl-α-D-glucopyranuronic acid methyl ester

Refernces