(±)-[[2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid MonoMethyl Ester

Base Information Edit

Chemical Name:(±)-[[2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid MonoMethyl Ester
CAS No.:123155-85-1
Molecular Formula:C10H16N5O4P
Molecular Weight:301.242
Hs Code.:
Mol file:123155-85-1.mol

Synonyms:(±)-[[2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid MonoMethyl Ester;Tenofovir MonoMethyl Ester

Suppliers and Price of (±)-[[2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid MonoMethyl Ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tenofovir Monomethyl Ester
2.5mg
$ 460.00

Medical Isotopes, Inc.
TenofovirMonomethylEster
25 mg
$ 2200.00

Total 1 raw suppliers

Chemical Property of (±)-[[2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid MonoMethyl Ester Edit

Chemical Property:

PSA：135.19000
LogP:1.18410
Storage Temp.:Hygroscopic, Refrigerator, Under Inert Atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

Tenofovir Monomethyl Ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses As acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor, Tenofovir MonoMethyl Ester can be used as an anti-HIV agent and Antiviral.

Technology Process of (±)-[[2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid MonoMethyl Ester

There total 2 articles about (±)-[[2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid MonoMethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14047-26-8,712-00-5
6-amino-α-methyl-9H-purine-9-ethanol

: 123155-85-1
methyl hydrogen ({[1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide

2: 1. NaH; 2. NaOH / 1. DMF, room temperature, 72 h; 2. DMF, H₂O, 50 deg C, 5 h

With sodium hydroxide; sodium hydride; In N,N-dimethyl-formamide;

Reference yield:

: 80792-13-8
dimethyl <<(p-tolylsulfonyl)oxy>methyl>phosphonate

: 123156-45-6
N'-[9-(2-Hydroxy-propyl)-9H-purin-6-yl]-N,N-dimethyl-formamidine

: 123155-85-1
methyl hydrogen ({[1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate

Guidance literature:: With sodium hydroxide; sodium hydride; Yield given. Multistep reaction; 1. DMF, room temperature, 72 h; 2. DMF, H₂O, 50 deg C, 5 h;