Furo[2,3-b]pyridin-5-aMine

Base Information

• Chemical Name: Furo[2,3-b]pyridin-5-aMine
• CAS No.: 34668-30-9
• Molecular Formula: C7H6N2O
• Molecular Weight: 134.137
• Hs Code.: 2934999090
• Mol file: 34668-30-9.mol

Synonyms:Furo[2,3-b]pyridin-5-aMine;5-AMinofuro[2,3-b]pyridine

Chemical Property of Furo[2,3-b]pyridin-5-aMine

Chemical Property:

• PSA: 52.05000
• LogP: 1.99120

Purity/Quality:

97% purity ^*data from raw suppliers

5-Aminofuro[2,3-b]pyridine 90+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Furo[2,3-b]pyridin-5-aMine

There total 2 articles about Furo[2,3-b]pyridin-5-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-nitrofuro<2,3-b>pyridine (34668-29-6) → furo[2,3-b]pyridin-5-ylamine (34668-30-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In benzene; at 25 ℃; for 0.75h;

Reference yield:

5-nitro-furo[2,3-b]pyridine-2-carboxylic acid (6563-65-1) → furo[2,3-b]pyridin-5-ylamine (34668-30-9)

Guidance literature:

Multi-step reaction with 2 steps

1: quinoline / Cu / 3 h / 185 - 200 °C

2: H₂ / Pd-C / benzene / 0.75 h / 25 °C

With quinoline; hydrogen; palladium on activated charcoal; copper; In benzene;

Reference yield:

furo[2,3-b]pyridin-5-ylamine (34668-30-9) → 5-bromofuro<2,3-b>pyridine (220957-39-1)

Guidance literature:

With hydrogen bromide; copper(I) bromide; sodium nitrite; Yield given; Multistep reaction; 1.) 0 deg C, 15 min;

DOI:10.1002/jhet.5570350611

upstream raw materials:

5-nitrofuro<2,3-b>pyridine

5-nitro-furo[2,3-b]pyridine-2-carboxylic acid

Downstream raw materials:

5-cyanofuro<2,3-b>pyridine

5-bromofuro<2,3-b>pyridine

5-formylfuro<2,3-b>pyridine

Refernces