Gallocatechin

Base Information Edit

Chemical Name:Gallocatechin
CAS No.:970-73-0
Deprecated CAS:528-54-1,13425-13-3,24987-87-9
Molecular Formula:C₁₅H₁₄O₇
Molecular Weight:306.272
Hs Code.:29339900
NSC Number:674038
UNII:HEJ6575V1X
DSSTox Substance ID:DTXSID10914220
Nikkaji Number:J277.679K
Wikipedia:Gallocatechol
Wikidata:Q72479982
NCI Thesaurus Code:C68451
Metabolomics Workbench ID:21832
ChEMBL ID:CHEMBL125743
Mol file:970-73-0.mol

Synonyms:epigallocatechin;epigallocatechol;gallocatechin;gallocatechol;gallocatechol, (2R-cis)-isomer;gallocatechol, (2R-trans)-isomer;gallocatechol, (2S-trans)-isomer

Suppliers and Price of Gallocatechin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(+)-Gallocatechin
1g
$ 1900.00

CSNpharm
(+)-Gallocatechin
1g
$ 1100.00

Crysdot
Gallocatechin 95+%
1g
$ 450.00

ChemScene
(+)-Gallocatechin 99.50%
20mg
$ 180.00

ChemScene
(+)-Gallocatechin 99.50%
10mg
$ 100.00

Cayman Chemical
(+)-Gallocatechin ≥95%
25mg
$ 99.00

Cayman Chemical
(+)-Gallocatechin ≥95%
50mg
$ 158.00

Cayman Chemical
(+)-Gallocatechin ≥95%
100mg
$ 297.00

Arctom
(+)-Gallocatechin ≥98%
20mg
$ 238.00

Arctom
(+)-Gallocatechin
10mg
$ 130.91

Total 51 raw suppliers

Chemical Property of Gallocatechin Edit

Chemical Property:

Melting Point:218 °C(Solv: water (7732-18-5))
Boiling Point:685.6 °C at 760 mmHg
PKA:9.02±0.15(Predicted)
Flash Point:368.5 °C
PSA：130.61000
Density:1.695 g/cm³
LogP:1.25170
Storage Temp.:2-8°C
Solubility.:H2O: 5?mg/mL with brief sonication
XLogP3:0
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:306.07395278
Heavy Atom Count:22
Complexity:380

Purity/Quality:

99%, ^*data from raw suppliers

(+)-Gallocatechin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O
Isomeric SMILES:C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O
Description (+)-Gallocatechin is a polyphenol and flavonoid that has been isolated from the leaves of tea plants and has diverse biological activities. It inhibits the adherence of P. gingivalis onto human buccal epithelial cells by more than 50% when used at a concentration of 250 μg/ml. (+)-Gallocatechin has antimutagenic properties in UV-irradiated E. coli cells. It inhibits cell death induced by D-galactosamine and TNF-α in primary cultured mouse hepatocytes by 29.9% when used at a concentration of 80 μM. (+)-Gallocatechin (100 μM) inhibits HCT116 colorectal cancer cell proliferation by 57%.
Uses (+)-Gallocatechin is antioxidant isomer of (-)-Gallocatechin (G188990), a potential cancer chemopreventive agent that inhibits the growth and adherence of P. gingivalis onto the buccal epithelial cells. An epimer of (-)-Epigallocatechin (E588940).

Technology Process of Gallocatechin

There total 48 articles about Gallocatechin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 2596-50-1,4233-96-9,5127-64-0,19065-20-4,107965-88-8,137766-94-0,989-51-5
(-)-epigallocathechin gallate

: 970-73-0,1617-55-6,3371-27-5,13425-13-3,136892-45-0,970-74-1,98032-84-9
epigallocatechin

Guidance literature:: With tannase; In water; at 35 ℃; for 12h; Enzymatic reaction;
DOI:10.1016/j.tetlet.2020.151601

Reference yield: 72.0%

: 332386-74-0
(-)-(2R,3R)-cis-5,7-bis(benzyloxy)-2-[3,4,5-tris(benzyloxy)phenyl]chroman-3-ol

: 970-73-0,1617-55-6,3371-27-5,13425-13-3,136892-45-0,970-74-1,98032-84-9
epigallocatechin

Guidance literature:: With 20% palladium hydroxide on carbon; hydrogen; In tetrahydrofuran; methanol; water; at 20 ℃; for 5h;
DOI:10.1039/c003464a

Reference yield: 51.0%

: 1449477-39-7
C₃₀H₃₈O₁₀

: 970-73-0,1617-55-6,3371-27-5,13425-13-3,136892-45-0,970-74-1,98032-84-9
epigallocatechin

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 - 20 ℃; for 2.5h; Inert atmosphere;
DOI:10.1002/asia.201201168