Ethoxyacetic acid 1-methylethyl ester

Base Information

• Chemical Name: Ethoxyacetic acid 1-methylethyl ester
• CAS No.: 54063-13-7
• Molecular Formula: C7H14O3
• Molecular Weight: 146.186
• Mol file: 54063-13-7.mol

Synonyms:Ethoxyacetic acid 1-methylethyl ester;Ethoxyacetic acid isopropyl ester

Chemical Property of Ethoxyacetic acid 1-methylethyl ester

Chemical Property:

• PSA: 35.53000
• LogP: 0.97450

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethoxyacetic acid 1-methylethyl ester

There total 2 articles about Ethoxyacetic acid 1-methylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3-oxapentanoic acid (627-03-2) + isopropyl alcohol (67-63-0,8013-70-5) → isopropyl 2-ethoxyacetate (54063-13-7)

Guidance literature:

for 12h; Reflux;

DOI:10.1016/j.tet.2015.12.046

Reference yield:

→ isopropyl 2-ethoxyacetate (54063-13-7)

Guidance literature:

aus Aethyldiazoacetat (UV-Licht) in Propanol-(2) ;

DOI:10.1021/ja01008a052

Reference yield: 96.0%

isopropyl 2-ethoxyacetate (54063-13-7) + rac-methylbenzylamine (618-36-0) → (R)-2-ethoxy-N-(1-phenylethyl)acetamide

Guidance literature:

With ammonium formate; lipase B from Candida antarctica; In tert-Amyl alcohol; toluene; at 60 ℃; for 16h; under 1551.49 Torr; Reagent/catalyst; Temperature; Catalytic behavior; Enzymatic reaction;

DOI:10.1021/acs.orglett.8b03676

upstream raw materials:

3-oxapentanoic acid

isopropyl alcohol

Downstream raw materials:

Ethoxy-(ethoxy-phenyl-phosphinoylsulfanyl)-acetic acid isopropyl ester

(S)-1-phenyl-ethylamine

(R)-1-phenyl-ethyl-amine

(S)-N-acetyl-1-phenylethylamine

Refernces