2-Methyl-6-furfurylidenecyclohexanone

Base Information

• Chemical Name: 2-Methyl-6-furfurylidenecyclohexanone
• CAS No.: 56053-07-7
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol file: 56053-07-7.mol

Synonyms:2-(2-Furanylmethylene)-6-methylcyclohexanone;2-Furfurylidene-6-methylcyclohexanone;2-Methyl-6-furfurylidenecyclohexanone

Chemical Property of 2-Methyl-6-furfurylidenecyclohexanone

Chemical Property:

• Melting Point: 51 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 306.6±31.0 °C(Predicted)
• PSA: 30.21000
• Density: 1.096±0.06 g/cm3(Predicted)
• LogP: 3.05210

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methyl-6-furfurylidenecyclohexanone

There total 2 articles about 2-Methyl-6-furfurylidenecyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

furfural (98-01-1) + 2-Methylcyclohexanone (583-60-8) → 2-[1-Furan-2-yl-meth-(E)-ylidene]-6-methyl-cyclohexanone (56053-07-7)

Guidance literature:

With potassium fluoride; tetramethylorthosilicate; In N,N-dimethyl-formamide; at 55 ℃; for 15h;

DOI:10.1055/s-1983-30309

Reference yield:

furfural (98-01-1) + 2-Methylcyclohexanone (583-60-8) → (+/-)-2-((Ξ)-furfurylidene)-6-methyl-cyclohexanone (56053-07-7)

Guidance literature:

With sodium methylate;

DOI:10.1021/ja01579a047

Reference yield: 85.0%

3-tolualdehyde N-Cbz imine (1092775-03-5) + (+/-)-2-((Ξ)-furfurylidene)-6-methyl-cyclohexanone (56053-07-7) → C28H29NO4

Guidance literature:

With (R,R)-(-)-2,6-bis[2-(hydroxyldiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenole; diethylzinc; In tetrahydrofuran; hexane; at 60 ℃; for 16h; stereoselective reaction; Molecular sieve;

DOI:10.1021/acscatal.8b04685

upstream raw materials:

furfural

2-Methylcyclohexanone

Downstream raw materials:

5-(3-methyl-2-oxo-cyclohexyl)-4-oxo-valeric acid

Refernces

• 1、 Chuit, C.,Corriu, R. J. P.,Reye, C.. "Aldol Condensations Promoted by a Tetraalkoxysilane in the Presence of Fluoride Ions". . p. 294 - 297. Retrieved 2007/10/02.