(2Z)-2-[(4-methoxyphenyl)imino]-1,2-diphenylethanone

Base Information

• Chemical Name: (2Z)-2-[(4-methoxyphenyl)imino]-1,2-diphenylethanone
• CAS No.: 4198-96-3
• Molecular Formula: C21H17NO2
• Molecular Weight: 315.371
• Mol file: 4198-96-3.mol

Synonyms:(2Z)-2-[(4-Methoxyphenyl)imino]-1, 2-diphenylethanone;

Chemical Property of (2Z)-2-[(4-methoxyphenyl)imino]-1,2-diphenylethanone

Chemical Property:

• Vapor Pressure: 1.91E-09mmHg at 25°C
• Refractive Index: 1.575
• Boiling Point: 481.9 °C at 760 mmHg
• Flash Point: 201.4 °C
• Density: 1.07 g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2Z)-2-[(4-methoxyphenyl)imino]-1,2-diphenylethanone

There total 15 articles about (2Z)-2-[(4-methoxyphenyl)imino]-1,2-diphenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-((4-methoxyphenyl)imino)-1,1-diphenylethan-1-ol → (R)-2-[(4-methoxyphenyl)amino]-1,2-diphenylethan-1-one + 2-((4-methoxyphenyl)imino)-1,2-diphenylethan-1-one (4198-96-3)

Guidance literature:

With C₆₈H₄₆N₂O₄Zr; In toluene; at 80 ℃; for 2h;

DOI:10.1021/ja5065685

Reference yield: 81.0%

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) + 4-methoxy-aniline (104-94-9) → 2-((4-methoxyphenyl)imino)-1,2-diphenylethan-1-one (4198-96-3)

Guidance literature:

With tris(pentafluorophenyl)borate; In nitromethane; at 120 ℃; for 12h;

Reference yield: 80.0%

4-methoxy-aniline (104-94-9) + benzil (134-81-6) → 2-((4-methoxyphenyl)imino)-1,2-diphenylethan-1-one (4198-96-3)

Guidance literature:

rac-methylbenzylamine; zinc(II) chloride; In xylene; for 6h; Heating;

DOI:10.1055/s-1982-30039

upstream raw materials:

α-chloro-α-(chlorosulfenyl)benzyl phenyl ketone

4-methoxy-aniline

benzil

2-((4-methoxyphenyl)amino)-1,2-diphenylethan-1-one

Downstream raw materials:

[3-(4-Chloro-phenyl)-4-(4-methoxy-phenyl)-5-phenyl-4,5-dihydro-[1,2,4]oxadiazol-5-yl]-phenyl-methanone

4-benzoyl-3,4-diphenyl-1-(4-methoxyphenyl)-2-azetidinone

[4-(4-Methoxy-phenyl)-3,5-diphenyl-4,5-dihydro-[1,2,4]oxadiazol-5-yl]-phenyl-methanone

2-((4-methoxyphenyl)amino)-1,2-diphenylethan-1-one

Refernces

• 1、 Zhang, Xin,Dai, Yijing,Wulff, William D.. "The Acceleration of the Rearrangement of α-Hydroxy Aldimines by Lewis or Bronsted Acids". . p. 2015 - 2018. Retrieved 2018/09/18.
• 2、 Buxton, Craig S.,Blakemore, David C.,Bower, John F.. "Reductive Coupling of Acrylates with Ketones and Ketimines by a Nickel-Catalyzed Transfer-Hydrogenative Strategy". supporting information. p. 13824 - 13828. Retrieved 2017/10/24.