4-AMino-2-chlorobenzothiazole

Base Information

• Chemical Name: 4-AMino-2-chlorobenzothiazole
• CAS No.: 855283-00-0
• Molecular Formula: C₇H₅ClN₂S
• Molecular Weight: 184.649
• Hs Code.: 2934200090
• Mol file: 855283-00-0.mol

Synonyms:4-AMino-2-chlorobenzothiazole

Chemical Property of 4-AMino-2-chlorobenzothiazole

Chemical Property:

• PSA: 67.15000
• LogP: 3.11310

Purity/Quality:

≥99% ^*data from raw suppliers

2-Chlorobenzo[d]thiazol-4-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMino-2-chlorobenzothiazole

There total 5 articles about 4-AMino-2-chlorobenzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-nitrophenyl)thiourea (51039-84-0) → 2-chloro-benzothiazol-4-ylamine (855283-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine; CHCl₃ / Behandeln des Reaktionsprodukts mit wss. Bisulfit

2: NaNO₂; aqueous HNO₃; H₃PO₄ / anschliessend Einwirkung von Kupfer in wss. HCl

With chloroform; phosphoric acid; bromine; nitric acid; sodium nitrite;

DOI:10.1002/hlca.19400230141

Reference yield:

2-chloro-4-nitrobenzothiazole (3507-30-0) → 2-chloro-benzothiazol-4-ylamine (855283-00-0)

Guidance literature:

With water; nickel; benzene; Hydrogenation;

DOI:10.1002/hlca.19400230141

Reference yield:

→ 2-chloro-benzothiazol-4-ylamine (855283-00-0) + 2-chloro-4-nitrobenzothiazole (3507-30-0)

Guidance literature:

With phosphoric acid; nitric acid; Behandeln der Diazoniumsalz-Loesung mit konz. wss. HCl und Kupfer;

DOI:10.1002/hlca.19400230141

upstream raw materials:

2-amino-4-nitrobenzothiazole

2-chloro-4-nitrobenzothiazole

N-(2-nitrophenyl)thiourea

Downstream raw materials:

thiazolo[5,4-h]quinoline

4-aminobenzothiazol