rac Cinacalcet HCl

Base Information Edit

Chemical Name:rac Cinacalcet HCl
CAS No.:1025064-33-8
Molecular Formula:C22H22F3N
Molecular Weight:357.419
Hs Code.:
Mol file:1025064-33-8.mol

Synonyms:rac Cinacalcet HCl;rac Cinacalcet;rac-Cinacalcet Hydrochloride;N-(1-(naphthalen-2-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Suppliers and Price of rac Cinacalcet HCl

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of rac Cinacalcet HCl Edit

Chemical Property:

Boiling Point:440.9±45.0 °C(Predicted)
PKA:9.19±0.29(Predicted)
PSA：12.03000
Density:1.154±0.06 g/cm3(Predicted)
LogP:6.53290

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of rac Cinacalcet HCl

There total 3 articles about rac Cinacalcet HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1206633-34-2
C₂₃H₂₄F₃N

: 1025064-33-8,694495-47-1
α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine

Guidance literature:: With hydrogen; 5% Pd(II)/C(eggshell); In methanol; at 25 - 30 ℃; under 760.051 Torr;

Reference yield:

: 1025064-44-1,955371-05-8
N-[1-(naphthalen-1-yl)ethyl]-3-(3-trifluoromethylphenyl)propanamide

: 1025064-33-8,694495-47-1
α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine

Guidance literature:: N-[1-(naphthalen-1-yl)ethyl]-3-(3-trifluoromethylphenyl)propanamide; With lithium aluminium tetrahydride; In tetrahydrofuran; at 30 - 65 ℃; for 3.33333h;

With water; ethyl acetate; In tetrahydrofuran; at 5 - 10 ℃; for 0.166667 - 0.25h;