Thiocarbonyl-carbamidsaeure-phenylester

Base Information

• Chemical Name: Thiocarbonyl-carbamidsaeure-phenylester
• CAS No.: 6374-24-9
• Molecular Formula: C8H5NO2S
• Molecular Weight: 179.199
• Mol file: 6374-24-9.mol

Synonyms:Thiocarbonyl-carbamidsaeure-phenylester;Phenoxycarbonyl isothiocyanate

Chemical Property of Thiocarbonyl-carbamidsaeure-phenylester

Chemical Property:

• Boiling Point: 65-68 °C(Press: 0.07 Torr)
• PSA: 70.75000
• Density: 1.19±0.1 g/cm3(Predicted)
• LogP: 2.28820

Purity/Quality:

98%min ^*data from raw suppliers

THIOCARBONYL CARBAMIDSAEURE PHENYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Thiocarbonyl-carbamidsaeure-phenylester

There total 6 articles about Thiocarbonyl-carbamidsaeure-phenylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

potassium thioacyanate (333-20-0) + phenyl chloroformate (1885-14-9) → phenoxycarbonyl isothiocyanate (6374-24-9)

Guidance literature:

In toluene; acetonitrile; for 48h;

DOI:10.1021/jo991458q

Reference yield: 85.0%

aqueous sodium thiocyanate + phenyl chloroformate (1885-14-9) → phenoxycarbonyl isothiocyanate (6374-24-9)

Guidance literature:

In quinoline;

Reference yield:

sodium thiocyanide (540-72-7) + phenyl chloroformate (1885-14-9) → phenoxycarbonyl isothiocyanate (6374-24-9)

Guidance literature:

In quinoline;

upstream raw materials:

potassium thioacyanate

phenyl chloroformate

sodium thiocyanide

ammonium thiocyanate

Downstream raw materials:

μ-imido-1-thio-dicarbonic acid-1-O-ethyl ester-2-phenyl ester

phenyl N-(2-thiazolyl)-carbamate

C₂₆H₂₄N₄O₆S

3-imino-2-methoxycarbonyl-N-phenoxycarbonylthiobutyramide

Refernces

• 1、 -. "Synthesis method of 2-amino-5, 8-dimethoxy[1, 2, 4]triazolo[1, 5-c]pyrimidine". Paragraph 0011; 0027; 0028. . Retrieved 2017/01/02.
• 2、 -. "NOVEL 2,3-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTIPSYCHOTIC AGENTS". Page/Page column 42-43. . Retrieved 2008/12/04.