1-cyanoethyl acetate

Base Information

• Chemical Name: 1-cyanoethyl acetate
• CAS No.: 15657-96-2
• Molecular Formula: C5H7 N O2
• Molecular Weight: 113.116
• Mol file: 15657-96-2.mol

Synonyms:Lactonitrile,acetate (6CI,7CI); Lactonitrile, acetate (ester) (8CI); 1-Cyanoethyl acetate;2-(Acetyloxy)propanenitrile; 2-Acetoxypropanenitrile; 2-Acetoxypropionitrile;NSC 71940

Chemical Property of 1-cyanoethyl acetate

Chemical Property:

• Vapor Pressure: 1.27mmHg at 25°C
• Boiling Point: 173.4°Cat760mmHg
• Flash Point: 67°C
• Density: 1.044g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-cyanoethyl acetate

There total 28 articles about 1-cyanoethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

ethylidene diacetate (542-10-9) + potassium cyanide (151-50-8) → 1-cyanoethyl acetate (15657-96-2)

Guidance literature:

In dimethyl sulfoxide; at 20 ℃; for 48h;

DOI:10.1021/ol005535b

Reference yield: 82.0%

trimethylsilyl cyanide (7677-24-9) + ethylidene diacetate (542-10-9) → 1-cyanoethyl acetate (15657-96-2)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at -78 - 20 ℃;

DOI:10.1021/ol005535b

Reference yield: 75.0%

vinyl acetate (108-05-4,9003-20-7) + acrylonitrile (107-13-1,25014-41-9) → 1-cyanoethyl acetate (15657-96-2)

Guidance literature:

With ruthenium hydroxide trichloride; In dichloromethane; at 160 ℃; for 3h; Autoclave; Inert atmosphere;

DOI:10.1134/S1070428011020011

upstream raw materials:

Ketene

2-hydroxy-propionitrile

vinyl acetate

hydrogen cyanide

Downstream raw materials:

acrylonitrile

ethyl 2-(2-oxo-1-cyano-2-ethoxyethylidene)-cyclohexanecarboxylate

1-cyano-4-oxo-2,6-diphenyl-cyclohexanecarboxylic acid methyl ester

hydrogen cyanide

Refernces

• 1、 Sandberg, Marcel,Sydnes, Leiv K.. "The chemistry of acylals. 3. Cyanohydrin esters from acylals with cyanide reagents". . p. 687 - 689. Retrieved 2007/10/03.
• 2、 -. "Processes for producing alpha -cyanohydrin esters and alpha -hydroxy acids". . . Retrieved 2008/06/13.