LURBINECTEDIN

Base Information

• Chemical Name: LURBINECTEDIN
• CAS No.: 497871-47-3
• Molecular Formula: C41H44N4O10S
• Molecular Weight: 784.87
• Mol file: 497871-47-3.mol

Synonyms:LURBINECTEDIN

Chemical Property of LURBINECTEDIN

Chemical Property:

• PKA: 9.79±0.40(Predicted)
• PSA: 189.58000
• Density: 1.55±0.1 g/cm3(Predicted)
• LogP: 4.39350

Purity/Quality:

99% ^*data from raw suppliers

Lurbinectedin >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Lurbinectedin is a synthetic tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogue with potential antineoplastic activity. Lurbinectedin covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death. Lurbinectedin was approved for medical use in the United States in June 2020.
• Uses: Lurbinectedin is being developed for the treatment of various cancers. It has been granted approval for treatment of metastatic small cell lung cancer.