TRIMETHOPRIM-D9 MAJOR

Base Information

• Chemical Name: TRIMETHOPRIM-D9 MAJOR
• CAS No.: 1189460-62-5
• Molecular Formula: C₁₄H₁₈N₄O₃
• Molecular Weight: 304.211
• Mol file: 1189460-62-5.mol

Synonyms:TRIMETHOPRIM-D9 MAJOR;2,4-Diamino-5-(3',4',5'-trimethoxy-d9-benzyl)pyrimidine;5-[(3,4,5-Trimethoxy-d9-phenyl)methyl]-2,4-pyrimidinediamine;Instalac-d9;Monotrim-d9;Proloprim-d9;Syraprim-d9;Tiempe-d9

Chemical Property of TRIMETHOPRIM-D9 MAJOR

Chemical Property:

• Melting Point: 210-212°C
• PSA: 106.97000
• LogP: 1.11780
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

Trimethoprim-d9 Major ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Deuterated Trimethoprim, an antibacterial. contains 90% D9, 10% D6 and no D0 Deuterated Trimethoprim, an antibacterial.contains 90% D9, 10% D6 and no D0

Technology Process of TRIMETHOPRIM-D9 MAJOR

There total 1 articles about TRIMETHOPRIM-D9 MAJOR which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine (738-70-5) → C14H4(2)H14N4O3 (1189923-38-3,1189460-62-5)

Guidance literature:

With platinum on carbon; palladium 10% on activated carbon; hydrogen; water-d2; at 180 ℃; for 34h;

DOI:10.1002/jlcr.1848

upstream raw materials:

5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine

Refernces