Methyl[(2-methyl-1,3-thiazol-5-yl)methyl]amine

Base Information

• Chemical Name: Methyl[(2-methyl-1,3-thiazol-5-yl)methyl]amine
• CAS No.: 63139-99-1
• Molecular Formula: C6H10N2S
• Molecular Weight: 142.22
• Hs Code.: 2934100090
• European Community (EC) Number: 827-876-4
• ChEMBL ID: CHEMBL4538125
• DSSTox Substance ID: DTXSID701296134
• Mol file: 63139-99-1.mol

Synonyms:methyl[(2-methyl-1,3-thiazol-5-yl)methyl]amine;63139-99-1;N-methyl-1-(2-methyl-1,3-thiazol-5-yl)methanamine;CHEMBL4538125;SCHEMBL11610869;DTXSID701296134;N,2-Dimethyl-5-thiazolemethanamine;AKOS009097773;EN300-44959;G28145;Z432733330

Chemical Property of Methyl[(2-methyl-1,3-thiazol-5-yl)methyl]amine

Chemical Property:

• Boiling Point: 207.1±15.0 °C(Predicted)
• PKA: 8.68±0.10(Predicted)
• PSA: 53.16000
• Density: 1.093±0.06 g/cm3(Predicted)
• LogP: 1.56180
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 142.05646950
• Heavy Atom Count: 9
• Complexity: 87.1

Purity/Quality:

methyl[(2-methyl-1,3-thiazol-5-yl)methyl]amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC=C(S1)CNC

Technology Process of Methyl[(2-methyl-1,3-thiazol-5-yl)methyl]amine

There total 1 articles about Methyl[(2-methyl-1,3-thiazol-5-yl)methyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylthiazole-4-carboxyaldehyde (1003-60-7) + methylamine hydrochloride (593-51-1) → N,2-dimethyl-5-thiazole-methane-amine (63139-99-1)

Guidance literature:

methylamine hydrochloride; With potassium carbonate; In methanol; at 20 ℃; for 0.5h;

2-methylthiazole-4-carboxyaldehyde; In methanol; at 20 ℃; for 1h;

With methanol; sodium tetrahydroborate; at 0 - 20 ℃; for 3h;

DOI:10.1021/acs.jmedchem.6b01196

upstream raw materials:

2-methylthiazole-4-carboxyaldehyde

methylamine hydrochloride

Refernces