(S)-γ-Methylhydrocinnamyl alcohol

Base Information

• Chemical Name: (S)-γ-Methylhydrocinnamyl alcohol
• CAS No.: 2031-46-1
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.221
• Mol file: 2031-46-1.mol

Synonyms:(3S)-3-Phenyl-1-butanol;(S)-3-Phenyl-1-butanol;(S)-γ-Methylhydrocinnamyl alcohol;[S,(+)]-3-Phenyl-1-butanol

Chemical Property of (S)-γ-Methylhydrocinnamyl alcohol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-γ-Methylhydrocinnamyl alcohol

There total 94 articles about (S)-γ-Methylhydrocinnamyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(S)-2-phenylbutanoic acid (4593-90-2,772-15-6) → (3S)-3-phenylbutan-1-ol (2031-46-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jo00177a047

Reference yield: 99.0%

(3S)-3-phenylbutanal (16251-77-7,42307-58-4,108211-22-9,53531-19-4) → (3S)-3-phenylbutan-1-ol (2031-46-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.166667h;

DOI:10.1039/b305623f

Reference yield: 99.0%

(R)-3-phenylbutyric acid (772-14-5) → (R)-3-phenylbutanol (2031-46-1,2722-36-3,86495-15-0,1126-07-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jo00177a047

upstream raw materials:

3-phenyl-1-butanol

(R)-3-phenylbutyric acid

(R)-2-(1Ξ,2E)-but-2-enylideneamino-3,3-dimethyl-butyric acid tert-butyl ester

3-phenylbut-1-ene

Downstream raw materials:

(S)-3-phenylbutyl bromide

(3S)-3-phenylbutanal

5-acetyl-6-hydroxy-4-methyl-7-[3-R-(3-(phenyl)butoxy)]benzofuran

(-)-R-5-Phenylhexansaeure

Refernces

• 1、 Cabré, Albert,Lledós, Agustí,Rafael, Sergi,Riera, Antoni,Sciortino, Giuseppe,Ujaque, Gregori,Verdaguer, Xavier. "Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols". supporting information. p. 7521 - 7527. Retrieved 2020/03/24.
• 2、 Zhou, Yujing,Bandar, Jeffrey S.,Liu, Richard Y.,Buchwald, Stephen L.. "CuH-Catalyzed Asymmetric Reduction of α,β-Unsaturated Carboxylic Acids to β-Chiral Aldehydes". . p. 606 - 609. Retrieved 2018/01/26.