L-NORADRENALINE HYDROCHLORIDE

Base Information

• Chemical Name: L-NORADRENALINE HYDROCHLORIDE
• CAS No.: 329-56-6
• Molecular Formula: C8H11 N O3 . Cl H
• Molecular Weight: 205.641
• Hs Code.: 2922509090
• Mol file: 329-56-6.mol

Synonyms:1,2-Benzenediol,4-(2-amino-1-hydroxyethyl)-, hydrochloride, (R)-; 1,2-Benzenediol,4-[(1R)-2-amino-1-hydroxyethyl]-, hydrochloride (9CI); Benzyl alcohol, a-(aminomethyl)-3,4-dihydroxy-,hydrochloride, (-)- (8CI); (-)-Noradrenaline hydrochloride; (-)-Norepinephrinehydrochloride; Arterenol hydrochloride; Aterenol; Noradrenaline hydrochloride;Norepinephrine hydrochloride; R-(-)-Noradrenaline hydrochloride;R-(-)-Norepinephrine monohydrochloride; l-Arterenol hydrochloride;l-Noradrenaline hydrochloride; l-Norepinephrine hydrochloride

Chemical Property of L-NORADRENALINE HYDROCHLORIDE

Chemical Property:

• Melting Point: ~150 °C (dec.)
• Boiling Point: 442.6°Cat760mmHg
• Flash Point: 221.5°C
• PSA: 86.71000
• Density: 1.397g/cm³
• LogP: 1.59220
• Storage Temp.: 2-8°C
• Solubility.: Very soluble in water, slightly soluble in ethanol (96 per cent). It becomes coloured on exposure to air and light.

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-NorepinephrineHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T,C,F
• Statements: 25-34-11
• Safety Statements: 45-36/37/39-26-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Alpha-adrenoceptor agonist.

Technology Process of L-NORADRENALINE HYDROCHLORIDE

There total 2 articles about L-NORADRENALINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C44H36N4O12P2(2-)*C8H11NO3*H(1+) → norepinephrine hydrochloride (329-56-6) + C44H36N4O12P2(2-)

Guidance literature:

In d⁽⁴⁾-methanol; water-d2; Equilibrium constant;

DOI:10.1002/1521-3773(20010903)40:17<3148::AID-ANIE3148>3.0.CO;2-S

Reference yield:

N-{{7-[bis(carboxymethyl)amino]coumarin-4-yl}methyloxycarbonyl}-L-norepinephrine (1031721-23-9) → 7-[bis(carboxymethyl)amino]-4-(hydroxymethyl)coumarin (876275-37-5) + carbon dioxide (124-38-9,18923-20-1) + norepinephrine hydrochloride (329-56-6)

Guidance literature:

With potassium hydroxide; HEPES buffer; In acetonitrile; pH=7.2; Quantum yield; UV-irradiation;

DOI:10.1002/chem.200701142

Reference yield:

3-(1,6-dihydro-6-oxo-9H-purin-9-yl)-propanoic acid,4-nitrophenyl ester + norepinephrine hydrochloride (329-56-6) → AIT-297

Guidance literature:

With triethylamine; In chloroform; dimethyl sulfoxide;

upstream raw materials:

N-{{7-[bis(carboxymethyl)amino]coumarin-4-yl}methyloxycarbonyl}-L-norepinephrine

Downstream raw materials:

7-(1-Hydroxy-2-aminoethyl)-3,4-dihydro-5-hydroxy-2H-1,4-benzothiazine-3-carboxylic acid

5-S-Cysteinylepinephrine

Refernces

• 1、 Herm, Michael,Molt, Oliver,Schrader, Thomas. "Towards synthetic adrenaline receptors - Shape-selective adrenaline recognition in water". . p. 3148 - 3151. Retrieved 2007/10/03.