1-((4-Methylphenyl)azo)-2-naphthalenol

Base Information

• Chemical Name: 1-((4-Methylphenyl)azo)-2-naphthalenol
• CAS No.: 6756-41-8
• Molecular Formula: C17H14N2O
• Molecular Weight: 262.311
• NSC Number: 106296
• UNII: 35H0V3D0KK
• DSSTox Substance ID: DTXSID501031796,DTXSID001216547
• Nikkaji Number: J523.869B,J993.383B
• Wikidata: Q27256461
• ChEMBL ID: CHEMBL1993024
• Mol file: 6756-41-8.mol

Synonyms:1-((4-Methylphenyl)azo)-2-naphthalenol;6756-41-8;1-(4-Tolylazo)-2-naphthol;1-[(4-methylphenyl)diazenyl]naphthalen-2-ol;NSC106296;35H0V3D0KK;NSC-106296;CCRIS 4005;1-[(4-METHYLPHENYL)AZO]-2-NAPHTHALENOL;NSC 106296;UNII-35H0V3D0KK;NCIMech_000442;SCHEMBL4751325;CHEMBL1993024;SCHEMBL11143645;SCHEMBL23960849;1-P-TOLYLAZO-2-NAPHTHOL;JCZUIEHTNMQCRK-VHEBQXMUSA-N;DTXSID001216547;DTXSID501031796;1-(4-Methylphenylazo)-2-naphthol;CCG-35575;2-Naphthol, 1-(4-methylphenyl)azo-;AS-0387;2-NAPHTHOL, 1-(P-TOLYLAZO)-;NCI60_000147;PD011692;PD028154;-(4-Methylphenyldiazoniumyl)-2-naphtholate;1-((4-METHYLPHENYL)AZO)-2-NAPHTHOL;1-[(E)-(4-Methylphenyl)diazenyl]-2-naphthol #;2-NAPHTHALENOL, 1-((4-METHYLPHENYL)AZO)-;Q27256461;1,2-Naphthalenedione, 1-[(4-methylphenyl)hydrazone]-;1,2-Naphthalenedione, 1-[2-(4-methylphenyl)hydrazone];1-[(1E)-2-(4-methylphenyl)diazen-1-yl]naphthalen-2-ol;2-NAPHTHALENOL, 1-(2-(4-METHYLPHENYL)DIAZENYL)-;64022-28-2

Chemical Property of 1-((4-Methylphenyl)azo)-2-naphthalenol

Chemical Property:

• Vapor Pressure: 2.16E-07mmHg at 25°C
• Refractive Index: 1.624
• Boiling Point: 456.4 °C at 760 mmHg
• Flash Point: 299.9 °C
• Density: 1.15 g/cm³
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 262.110613074
• Heavy Atom Count: 20
• Complexity: 336

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)N=NC2=C(C=CC3=CC=CC=C32)O

Technology Process of 1-((4-Methylphenyl)azo)-2-naphthalenol

There total 27 articles about 1-((4-Methylphenyl)azo)-2-naphthalenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-(4-methylphenylazo)pyrrolidine (36651-88-4) + β-naphthol (135-19-3) → 1-(4-methylphenylazo)naphthalen-2-ol (6756-41-8)

Guidance literature:

With C₆H₉N₂O₂⁽¹⁺⁾*C₇H₇O₃S^(1-); In water; at 20 ℃; for 4h; Green chemistry;

DOI:10.1016/j.dyepig.2018.05.073

Reference yield: 98.0%

p-toluidine (106-49-0,12221-03-3) + β-naphthol (135-19-3) → 1-(4-methylphenylazo)naphthalen-2-ol (6756-41-8)

Guidance literature:

p-toluidine; With hydrogenchloride; In water; at 0 - 5 ℃; for 0.0833333h;

β-naphthol; In water; for 0.0833333h;

DOI:10.2174/1570178614666170321125216

Reference yield: 96.0%

p-methylbenzenediazonium chloride (2028-84-4) + β-naphthol (135-19-3) → 1-(4-methylphenylazo)naphthalen-2-ol (6756-41-8)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 0.166667h; Ambient temperature;

DOI:10.1039/a605013a

upstream raw materials:

methanol

ethanol

p-methylbenzenediazonium chloride

sodium 2-naphtholate

Downstream raw materials:

Ru(an-Me)(Cl)(PPh₃)2

1,6-dinitro-2-naphthol

1-(2-(p-tolyl)hydrazono)naphthalen-2(1H)-one

acetic acid <1-(4-methylphenylazo)-naphthalen-2-ol> ester

Refernces

• 1、 Afifi, Tarek H.,Riyadh, Sayed M.,Deawaly, Anwar A.,Naqvi, Arshi. "Novel chromenes and benzochromenes bearing arylazo moiety: molecular docking, in-silico admet, in-vitro antimicrobial and anticancer screening". . p. 1471 - 1487. Retrieved 2019/07/08.
• 2、 Shomali, Ashkan,Valizadeh, Hassan,Noorshargh, Saeideh. "New generation of nitrite functionalized star-like polyvinyl imidazolium compound: Application as a nitrosonium source and three dimensional nanocatalyst for the synthesis of azo dyes". . p. 409 - 418. Retrieved 2017/07/24.