4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate hydrate

Base Information

• Chemical Name: 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate hydrate
• CAS No.: 915967-82-7
• Molecular Formula: C₂₉H₃₂Cl₂N₆*4H₂O*4H₃O₄P
• Molecular Weight: 999.561
• Mol file: 915967-82-7.mol

Synonyms:4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate hydrate;Piperaquine tetraphosphate tetrahydrate

Chemical Property of 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate hydrate

Chemical Property:

• Melting Point: 252 °C(dec.)
• PSA: 425.94000
• LogP: 1.45830
• Storage Temp.: room temp
• Sensitive.: Hygroscopic
• Solubility.: H2O: ≥10mg/mL

Purity/Quality:

98%,99%, ^*data from raw suppliers

Piperaquine Tetraphosphate Tetrahydrate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate hydrate

There total 1 articles about 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate hydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-bis[1-(7-chloroquinolin-4-yl)piperazin-4-yl]propane (4085-31-8,83764-65-2) → 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propanephosphate (915967-82-7)

Guidance literature:

With phosphoric acid; water; at 5 - 15 ℃; for 4 - 5h;

upstream raw materials:

1,3-bis[1-(7-chloroquinolin-4-yl)piperazin-4-yl]propane

Refernces