Technology Process of 5-Fluoro-1-methoxy-2-methyl-3-nitrobenzene
There total 5 articles about 5-Fluoro-1-methoxy-2-methyl-3-nitrobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride / 1,4-dioxane / 2 h / 15 °C
2: sulfuric acid; sodium nitrite / water / 4 h / 0 - 115 °C
3: potassium carbonate / N,N-dimethyl-formamide / 0 - 20 °C
With
hydrogenchloride; sulfuric acid; potassium carbonate; sodium nitrite;
In
1,4-dioxane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sulfuric acid; nitric acid / 3 h / 0 - 15 °C
2: sodium sulfide / ethanol; water / 4.5 h / 25 °C
3: sulfuric acid; sodium nitrite / water / 4 h / 0 - 115 °C
4: potassium carbonate / N,N-dimethyl-formamide / 0 - 20 °C
With
sodium sulfide; sulfuric acid; nitric acid; potassium carbonate; sodium nitrite;
In
ethanol; water; N,N-dimethyl-formamide;
