Technology Process of 1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine
There total 12 articles about 1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: Et3N / toluene / 3 h / Heating
2: pyridine
3: H2, CaCO3 / 10percent Pd/C / CHCl3 / 18 h / 40 °C / 1034.3 Torr
4: 1.) Et3N, 2.) Et3N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h
5: CHCl3; propan-2-ol; dimethylformamide / 12 h / 50 °C
With
pyridine; water; hydrogen; triethylamine; calcium carbonate;
palladium on activated charcoal;
In
chloroform; N,N-dimethyl-formamide; isopropyl alcohol; toluene;
DOI:10.1021/jm00388a008
- Guidance literature:
-
Multi-step reaction with 4 steps
1: pyridine
2: H2, CaCO3 / 10percent Pd/C / CHCl3 / 18 h / 40 °C / 1034.3 Torr
3: 1.) Et3N, 2.) Et3N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h
4: CHCl3; propan-2-ol; dimethylformamide / 12 h / 50 °C
With
pyridine; water; hydrogen; triethylamine; calcium carbonate;
palladium on activated charcoal;
In
chloroform; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm00388a008
- Guidance literature:
-
Multi-step reaction with 3 steps
1: H2, CaCO3 / 10percent Pd/C / CHCl3 / 18 h / 40 °C / 1034.3 Torr
2: 1.) Et3N, 2.) Et3N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h
3: CHCl3; propan-2-ol; dimethylformamide / 12 h / 50 °C
With
water; hydrogen; triethylamine; calcium carbonate;
palladium on activated charcoal;
In
chloroform; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm00388a008
