4-Cyclopentyl-benzeneMethanol

Base Information

• Chemical Name: 4-Cyclopentyl-benzeneMethanol
• CAS No.: 171623-29-3
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Hs Code.: 2906290090
• Mol file: 171623-29-3.mol

Synonyms:4-Cyclopentyl-benzeneMethanol;(4-Cyclopentylphenyl)Methanol

Chemical Property of 4-Cyclopentyl-benzeneMethanol

Chemical Property:

• Boiling Point: 312.7±11.0 °C(Predicted)
• PKA: 14.48±0.10(Predicted)
• PSA: 20.23000
• Density: 1.057±0.06 g/cm3(Predicted)
• LogP: 2.83650
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

(4-Cyclopentylphenyl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Cyclopentyl-benzeneMethanol

There total 11 articles about 4-Cyclopentyl-benzeneMethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Methyl 4-cyclopentylbenzoate (160598-47-0) → (4-cyclopentylphenyl)methanol (171623-29-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 0.5h; Heating;

Reference yield: 81.0%

isopropyl 4-cyclopentylbenzoate → (4-cyclopentylphenyl)methanol (171623-29-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Inert atmosphere;

Reference yield:

1-(p-formylphenyl)cyclopentene (915016-86-3) → (4-cyclopentylphenyl)methanol (171623-29-3)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 10 ℃; for 3h;

upstream raw materials:

Methyl 4-cyclopentylbenzoate

Cyclopentyl bromide

cyclopentylbenzene

p-cyclopentylbenzoic acid

Refernces

• 1、 Nuzzi, Andrea,Fiasella, Annalisa,Ortega, Jose Antonio,Pagliuca, Chiara,Ponzano, Stefano,Pizzirani, Daniela,Bertozzi, Sine Mandrup,Ottonello, Giuliana,Tarozzo, Glauco,Reggiani, Angelo,Bandiera, Tiziano,Bertozzi, Fabio,Piomelli, Daniele. "Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies". supporting information. p. 138 - 159. Retrieved 2016/02/18.
• 2、 Byron, D. J.,Matharu, A. S.,Rees, M.,Wilson, R. C.. "Synthesis of Certain Mesogenic Azomethines Derived from 4-Cycloalkylanilines and from 4-Cycloalkylbenzaldehydes". . p. 229 - 238. Retrieved 2007/10/02.