Δ2-Cefepime

Base Information

• Chemical Name: Δ2-Cefepime
• CAS No.: 88040-25-9
• Molecular Formula: C₁₉H₂₄N₆O₅S₂
• Molecular Weight: 480.569
• Mol file: 88040-25-9.mol

Synonyms:Δ2-Cefepime;Δ2-CefepiMe Etherate;1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-en-3-yl]Methyl]-1-MethylpyrrolidiniuM Inner Salt Etherate;Δ2-CefepiMe Etherate Dihydrochloride Salt

Chemical Property of Δ2-Cefepime

Chemical Property:

• Melting Point: >151°C (dec.)
• PSA: 217.03000
• LogP: 0.42840
• Storage Temp.: Amber Vial, -20?C Freezer, Under Inert Atmosphere
• Solubility.: Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

Δ2-Cefepime ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: The Δ2-isomer of Cefepime (C242750), a new series of cephalosporins. Δ2-Cefepime is the Δ2-isomer of Cefepime (C242750), a new series of cephalosporins.

Technology Process of Δ2-Cefepime

There total 1 articles about Δ2-Cefepime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

cefepime (88040-23-7) → (6R,7R)-7-[2-(2-amino-4-thiazolyl)-2-(Z)-(methoxyimino)acetamido]-3-[(1-methyl-1-pyrrolidinium)methyl]-2-cephem-4-carboxylate (88040-25-9)

Guidance literature:

cefepime; With N-Trimethylsilylacetamide; In dichloromethane; for 0.5h;

With triethylamine; In dichloromethane; at 25 - 30 ℃; for 24h;

With hydrogenchloride; at 2 - 5 ℃; Further stages.;

upstream raw materials:

cefepime

Refernces