N,N'-Diisopropylphthalamide

Base Information

• Chemical Name: N,N'-Diisopropylphthalamide
• CAS No.: 38228-97-6
• Molecular Formula: C₁₄H₂₀N₂O₂
• Molecular Weight: 248.325
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID40357489
• Wikidata: Q82137415
• Mol file: 38228-97-6.mol

Synonyms:N,N'-Diisopropylphthalamide;38228-97-6;1-N,2-N-di(propan-2-yl)benzene-1,2-dicarboxamide;N1,N2-Diisopropylphthalamide;starbld0037367;Enamine_005971;Oprea1_201087;DTXSID40357489;WYYLYWSIWFBBLG-UHFFFAOYSA-N;HMS1410P09;N,N'-Diisopropylphthalamide, 95%;AKOS001033919;IDI1_008206;Phthalic acid, diamide, N,N'-diisopropyl;SR-01000025270;SR-01000025270-1;Z56756664

Chemical Property of N,N'-Diisopropylphthalamide

Chemical Property:

• Melting Point: 210-213 °C(lit.)
• Boiling Point: 462.8±28.0 °C(Predicted)
• PKA: 13.83±0.46(Predicted)
• Flash Point: 178.4oC
• PSA: 58.20000
• Density: 1.048±0.06 g/cm3(Predicted)
• LogP: 2.74480
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 248.152477885
• Heavy Atom Count: 18
• Complexity: 270

Purity/Quality:

N,N′-Diisopropylphthalamide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)NC(=O)C1=CC=CC=C1C(=O)NC(C)C

Technology Process of N,N'-Diisopropylphthalamide

There total 9 articles about N,N'-Diisopropylphthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-methoxyphthalimide (1914-20-1) + isopropylamine (75-31-0) → N1,N2-diisopropylphthalamide (38228-97-6)

Guidance literature:

for 6h; Ambient temperature;

Reference yield: 74.0%

3-(isopropylimino)-2-benzofuran-1(3H)-one (103606-36-6) + isopropylamine (75-31-0) → N1,N2-diisopropylphthalamide (38228-97-6)

Guidance literature:

In benzene; at 20 ℃;

Reference yield: 25.0%

isopropylamine (75-31-0) + Phthaloyl dichloride (88-95-9) → N1,N2-diisopropylphthalamide (38228-97-6)

Guidance literature:

In benzene; at 20 ℃;

upstream raw materials:

2-(2-bromoethyl)isoindoline-1,3-dione

isopropylamine

3-(isopropylimino)-2-benzofuran-1(3H)-one

Phthaloyl dichloride

Refernces

• 1、 Ganin, E. V.,Makarov, V. F.,Rozynov, B. V.. "FEATURES OF THE REACTION OF PHTHALOYL CHLORIDE WITH PRIMARY AMINES". . p. 1772 - 1777. Retrieved 2007/10/02.