alpha-Campholenol

Base Information

• Chemical Name: alpha-Campholenol
• CAS No.: 1901-38-8
• Molecular Formula: C10H18O
• Molecular Weight: 154.252
• Hs Code.: 2906199090
• European Community (EC) Number: 217-600-5
• UNII: 9H6329UALZ
• DSSTox Substance ID: DTXSID30862779
• Nikkaji Number: J13.018D
• Wikidata: Q27272553
• Metabolomics Workbench ID: 47173
• Mol file: 1901-38-8.mol

Synonyms:1901-38-8;alpha-Campholenol;2-(2,2,3-Trimethylcyclopent-3-en-1-yl)ethanol;2,2,3-Trimethylcyclopent-3-ene-1-ethanol;Campholenic alcohol;.alpha.-Campholenol;Campholenic alcohol, alpha-;Naturanol;3-Cyclopentene-1-ethanol, 2,2,3-trimethyl-;Campholenol, alpha-;FEMA No. 3741;alpha-campholenic alcohol;UNII-9H6329UALZ;2-(2,2,3-trimethylcyclopent-3-en-1-yl)ethan-1-ol;9H6329UALZ;EINECS 217-600-5;2,2,3-TRIMETHYL-3-CYCLOPENTENE-1-ETHANOL;EINECS 257-920-2;TRIMENOL;SCHEMBL1244992;FEMA 3741;DTXSID30862779;(+/-)-CAMPHOLENE ALCOHOL;CAMPHOLENE ALCOHOL, (+/-)-;2,2,3-Trimethyl-3-cyclopentene-1-ethanol, 9CI;2-(2,2,3-trimethyl-1-cyclopent-3-enyl)ethanol;3-Cyclopentene-1-ethanol, 2,2,3-trimethyl-, (R)-;Q27272553

Chemical Property of alpha-Campholenol

Chemical Property:

• Vapor Pressure: 0.00104mmHg at 25°C
• Refractive Index: 1.455
• Boiling Point: 209.337 °C at 760 mmHg
• PKA: 15.09±0.10(Predicted)
• Flash Point: 78.13 °C
• PSA: 20.23000
• Density: 0.889 g/cm³
• LogP: 2.36120
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 154.135765193
• Heavy Atom Count: 11
• Complexity: 168

Purity/Quality:

98%min ^*data from raw suppliers

2,2,3-TRIMETHYLCYCLOPENT-3-ENE-1-ETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CCC(C1(C)C)CCO

Technology Process of alpha-Campholenol

There total 18 articles about alpha-Campholenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

(RS)-(+/-)-ethyl (2,2,3-trimethyl-cyclopent-3-en-1-yl)acetate (81907-73-5,91200-41-8) → (RS)-(+/-)-2-(2,2,3-trimethyl-cyclopent-3-en-1-yl)ethanol (1901-38-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield: 60.0%

5,7,7-trimethyl-3-oxa-tricyclo[4.1.1.02,4]octane (25488-94-2) → (RS)-(+/-)-2-(2,2,3-trimethyl-cyclopent-3-en-1-yl)ethanol (1901-38-8)

Guidance literature:

With ammonia borane; C₂₈H₂₈Cl₂CoNP₂; erbium(III) triflate; In tetrahydrofuran; at 55 ℃; for 8h;

DOI:10.1021/acscatal.0c03294

Reference yield:

(3-chloromethyl-2,2-dimethyl-cyclopent-3-enyl)-acetaldehyde (63025-70-7) → (RS)-(+/-)-2-(2,2,3-trimethyl-cyclopent-3-en-1-yl)ethanol (1901-38-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 30 ℃; for 36h;

DOI:10.1016/0040-4020(82)85079-5

upstream raw materials:

2,3,3-Trimethyl-4-(methoxycarbonylmethyl)-cyclopenten

(3-chloromethyl-2,2-dimethyl-cyclopent-3-enyl)-acetaldehyde

exo-2,2-dimethyl-3-methylenebicyclo<2.2.1>heptan-5-ol

endo-2,2-dimethyl-3-methylenebicyclo<2.2.1>heptan-5-ol

Downstream raw materials:

campholenyc aldehyde

α-Campholenyl-p-toluolsulfonat

Refernces

• 1、 Yadav, J. S.,Patil, Dilip G.,Krishna, R. R.,Chawla, H. P. S.,Dev, Sukh. "HETEROLYTIC CLEAVAGE OF HOMOALLYLIC ALCOHOLS-I. FRAGMENTATION OF 6-HYDROXYCAMPHENE DERIVATIVES". . p. 1003 - 1007. Retrieved 1982.
• 2、 Mimoun. "Selective reduction of carbonyl compounds by polymethylhydrosiloxane in the presence of metal hydride catalysts". . p. 2582 - 2589. Retrieved 2007/10/03.