Dihydrobetulonicacidmethylester

Base Information

• Chemical Name: Dihydrobetulonicacidmethylester
• CAS No.: 20066-05-1
• Molecular Formula: C31H50O3
• Molecular Weight: 470.73
• Mol file: 20066-05-1.mol

Synonyms:Dihydrobetulonicacidmethylester;MethylDihydrobetulonate

Chemical Property of Dihydrobetulonicacidmethylester

Chemical Property:

• Melting Point: 192 - 193 °C (methanol)
• PSA: 43.37000
• LogP: 7.46600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dihydrobetulonicacidmethylester

There total 16 articles about Dihydrobetulonicacidmethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methyl betulonate (4356-31-4) → methyl dihydrobetulonate (20066-05-1)

Guidance literature:

With platinum(IV) oxide; hydrogen; In methanol; chloroform; for 8h; Inert atmosphere;

DOI:10.1134/S1070428009100078

Reference yield: 89.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 3-oxolupan-28-ic acid (25576-27-6) → methyl dihydrobetulonate (20066-05-1)

Guidance literature:

In diethyl ether; at 20 ℃;

DOI:10.1007/s11172-013-0028-y

Reference yield:

dihydromethylbetulinate (4550-88-3) → methyl dihydrobetulonate (20066-05-1)

Guidance literature:

With Jones reagent; In acetone;

DOI:10.13005/ojc/350331

upstream raw materials:

diazomethane

3-oxolupan-28-ic acid

dimethyl sulfate

methyl betulonate

Refernces

• 1、 Urban, Milan,Sarek, Jan,Kvasnica, Miroslav,Tislerova, Iva,Hajduch, Marian. "triterpenoid pyrazines and benzopyrazines with cytotoxic activity". . p. 526 - 532. Retrieved 2007.
• 2、 Spivak, A. Yu.,Nedopekina,Shakurova,Khalitova,Gubaidullin,Odinokov,Dzhemilev,Bel'Skii, Yu. P.,Bel'Skaya,Stankevich,Korotkaya,Khazanov. "Synthesis of lupane triterpenoids with triphenylphosphonium substituents and studies of their antitumor activity". . p. 188 - 198. Retrieved 2013.
• 3、 Ghosh, Pranab,Chakraborty, Prasanta. "Denomination of 2-bromo-3-keto triterpenoids using N,N-dimethylaniline". experimental part. p. 1037 - 1039. Retrieved 2012/04/04.