2-(2,6-DICHLOROPHENYL)ACETALDEHYDE

Base Information

• Chemical Name: 2-(2,6-DICHLOROPHENYL)ACETALDEHYDE
• CAS No.: 20973-90-4
• Molecular Formula: C8H6Cl2O
• Molecular Weight: 189.041
• Hs Code.: 2913000090
• Mol file: 20973-90-4.mol

Synonyms:2-(2,6-DICHLOROPHENYL)ACETALDEHYDE;2,6-dichlorobenzeneacetaldehyde

Chemical Property of 2-(2,6-DICHLOROPHENYL)ACETALDEHYDE

Chemical Property:

• Boiling Point: 269.4±25.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.317±0.06 g/cm3(Predicted)
• LogP: 2.73480

Purity/Quality:

99% ^*data from raw suppliers

2-(2,6-dichlorophenyl)acetaldehyde ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-41

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2,6-DICHLOROPHENYL)ACETALDEHYDE

There total 10 articles about 2-(2,6-DICHLOROPHENYL)ACETALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,6-dichlorophenylacetonitrile (3215-64-3) → 2-(2,6-dichlorophenyl)acetaldehyde (20973-90-4)

Guidance literature:

With diisobutylaluminium hydride; In hexane; toluene; at 0 ℃; for 0.5h;

Reference yield: 70.0%

2-(2,6-dichlorophenyl)ethan-1-ol (30595-79-0) → 2-(2,6-dichlorophenyl)acetaldehyde (20973-90-4)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield: 62.0%

1,3-Dichloro-2-chloromethyl-benzene (2014-83-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2-(2,6-dichlorophenyl)acetaldehyde (20973-90-4)

Guidance literature:

1,3-Dichloro-2-chloromethyl-benzene; With magnesium; In diethyl ether;

N,N-dimethyl-formamide; In diethyl ether;

DOI:10.1016/S0040-4039(99)01855-9

upstream raw materials:

2-(2,6-dichlorophenyl)ethan-1-ol

2,6-Dichlor-ω-dimethylaminostyrol

[(E)-2-(2,6-Dichloro-phenyl)-vinyl]-carbamic acid methyl ester

1,3-Dichloro-2-chloromethyl-benzene

Downstream raw materials:

N¹-(2,6-dichlorophenethyl)-N³,N³-dimethylpropane-1,3-diamine

6-Chloro-8-(2,6-dichloro-benzyl)-9H-purine

(2,6-dichlorophenyl)acetaldehyde oxime

2,6-dichlorophenylacetaldehyde dimethylacetal

Refernces

• 1、 -. "THERAPEUTIC COMPOUNDS". Paragraph 0400; 0401. . Retrieved 2018/08/30.
• 2、 -. "Nitrogen-heterocyclic compound and process for production thereof". Page column 15. . Retrieved 2010/01/30.