2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl

Base Information

• Chemical Name: 2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl
• CAS No.: 932033-57-3
• Molecular Formula: C34H42O2
• Molecular Weight: 482.706
• Hs Code.: 2918992090
• Mol file: 932033-57-3.mol

Synonyms:2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl;1,1'-(4,4'-DiMethoxy[1,1'-biphenyl]-3,3'-diyl)bistricyclo[3.3.1.13,7]decane;Adapalene Related CoMpound D;4,4′-Dimethoxy-3,3′-di(adamant-1-yl)biphenyl;Adapalene Related Compound D (25 mg) (4,4'-dimethoxy-3,3'-di(adamant-1-yl)biphenyl)

Chemical Property of 2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl

Chemical Property:

• PSA: 18.46000
• Density: 1.147±0.06 g/cm3(Predicted)
• LogP: 8.30640
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Dichloromethane (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

2,2’-Bis-(1-adamantyl)-4,4’-dimethoxybiphenyl ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl

There total 1 articles about 2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.83%

methyl 6-bromo-2-naphthoate (33626-98-1) + 2-(1-adamantyl)-4-bromoanisole (104224-63-7) → 3,3'-diadamantyl-4,4'-dimethoxybiphenyl (932033-57-3) + 6-(3-adamantan-1-yl-4-methoxyphenyl)naphthalene-2-carboxylic acid methyl ester (106685-41-0)

Guidance literature:

2-(1-adamantyl)-4-bromoanisole; With magnesium; ethylene dibromide; In tetrahydrofuran; at 45 - 55 ℃; for 1.5h;

With zinc(II) chloride; In tetrahydrofuran; at 20 - 25 ℃; for 1h;

methyl 6-bromo-2-naphthoate; 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; at 20 ℃; for 2h;

upstream raw materials:

methyl 6-bromo-2-naphthoate

2-(1-adamantyl)-4-bromoanisole

Refernces