7-Bromo-3,4-dichloroquinoline

Base Information

• Chemical Name: 7-Bromo-3,4-dichloroquinoline
• CAS No.: 1021435-01-7
• Molecular Formula: C₉H₄BrCl₂N
• Molecular Weight: 276.947
• Hs Code.: 2933499090
• Mol file: 1021435-01-7.mol

Synonyms:7-Bromo-3,4-dichloroquinoline;7-Bromo-3,4-dichloro-1-azanaphthalene

Chemical Property of 7-Bromo-3,4-dichloroquinoline

Chemical Property:

• PSA: 12.89000
• LogP: 4.30410

Purity/Quality:

97% ^*data from raw suppliers

7-Bromo-3,4-dichloroquinoline ^*data from reagent suppliers

Safty Information:

• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Bromo-3,4-dichloroquinoline

There total 2 articles about 7-Bromo-3,4-dichloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-bromo-3-chloroquinolin-4(1H)-one → 7-bromo-3,4-dichloroquinoline (1021435-01-7)

Guidance literature:

With trichlorophosphate; In 1,4-dioxane; at 90 ℃; for 2.5h;

Reference yield:

7-bromo-4(1H)-oxoquinoline (82121-06-0,956268-33-0) → 7-bromo-3,4-dichloroquinoline (1021435-01-7)

Guidance literature:

Multi-step reaction with 2 steps

1: N-chloro-succinimide; acetic acid / 5 h / 60 °C

2: trichlorophosphate / 1,4-dioxane / 2.5 h / 90 °C

With N-chloro-succinimide; acetic acid; trichlorophosphate; In 1,4-dioxane;

upstream raw materials:

7-bromo-4(1H)-oxoquinoline

Refernces