5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydrobenzimidazole-2-thione

Base Information Edit

Chemical Name:5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydrobenzimidazole-2-thione
CAS No.:68828-69-3
Molecular Formula:C₁₃H₇Cl₃N₂OS
Molecular Weight:345.636
Hs Code.:
UNII:ZB9HO25QQB
DSSTox Substance ID:DTXSID80403015
Wikidata:Q82206547
Mol file:68828-69-3.mol

Synonyms:68828-69-3;AC1N9P61;5-chloro-6-(2,3-dichlorophenoxy)-1,3-dihydrobenzimidazole-2-thione;ZB9HO25QQB;SCHEMBL8531381;DTXSID80403015;FUAVONSJNAMFPO-UHFFFAOYSA-N;TRICLABENDAZOLE METABOLITE M8;2H-Benzimidazole-2-thione, 5-chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-;5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-Benzimidazole-2-thione;5-Chloro-6-(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol;6-chloro-5(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol;TRICLABENDAZOLE FOR VETERINARY USE IMPURITY B [EP IMPURITY];5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-benzo[d]imidazole-2-thione;5-chloro-6-(2,3-dichlorophenoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione

Suppliers and Price of 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydrobenzimidazole-2-thione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydrobenzimidazole-2-thione Edit

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:343.934467
Heavy Atom Count:20
Complexity:387

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)Cl)Cl)OC2=C(C=C3C(=C2)NC(=S)N3)Cl

Technology Process of 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydrobenzimidazole-2-thione

There total 13 articles about 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydrobenzimidazole-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 75-15-0,12122-00-8
carbon disulfide

: 139369-42-9
4-chloro-5-(2,3-dichlorophenoxy)-1,2-phenylenediamine

: 68828-69-3
5-chloro-6-(2,3-dichlorophenoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione

Guidance literature:: In N,N-dimethyl-formamide; at 80 ℃; for 5h;
DOI:10.1039/P19920003129

Reference yield: 72.0%

: 75-15-0,12122-00-8
carbon disulfide

: 118353-04-1
4-chloro-5-(2,3-dichlorophenoxy)-2-nitroaniline

: 68828-69-3
5-chloro-6-(2,3-dichlorophenoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione

Guidance literature:: 4-chloro-5-(2,3-dichlorophenoxy)-2-nitroaniline; With trichlorosilane; triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

carbon disulfide; With potassium hydroxide; In ethanol; at 85 ℃; for 15.5h;

Reference yield:

: 145770-86-1
5-chloro-6-(2,3-dichlorophenoxy)-2H-benzimidazole-2-spirocyclohexane

: 68828-69-3
5-chloro-6-(2,3-dichlorophenoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / sodium dithionite / ethanol; H₂O / 0.5 h / Heating

2: 90 percent / dimethylformamide / 5 h / 80 °C

With sodium dithionite; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1039/P19920003129