CID 4640670

Base Information

• Chemical Name: CID 4640670
• CAS No.: 12192-57-3
• Molecular Formula: C6H11 Au O5 S
• Molecular Weight: 392.20
• Hs Code.: 2843300000
• European Community (EC) Number: 235-365-7
• NCI Thesaurus Code: C87435
• Wikipedia: Aurothioglucose
• Mol file: 12192-57-3.mol

Synonyms:Aureotan;Auromyose;Aurothioglucose;Aurothioglucose, beta D Isomer;Aurothioglucose, beta-D Isomer;Aurothioglucose, Sodium Salt, beta-D Isomer;B Oleosum, Solganal;beta-D Isomer Aurothioglucose;Gold 50;Gold Thioglucose;Gold-50;Gold50;Oleosum, Solganal B;Solganal;Solganal B Oleosum;Solganol;Thioglucose, Gold;Thioglucosoaurate

Chemical Property of CID 4640670

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 115.45000
• Density: g/cm³
• LogP: -2.01870
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble5mg/mL, clear
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 391.999290
• Heavy Atom Count: 13
• Complexity: 160

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ggt1 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 42/43
• Safety Statements: 22-36/37-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)[S-])O)O)O)O.[Au+]
• Description: Aurothioglucose is highly water soluble, and its aqueous solutions decompose on long standing. It therefore is available as a suspension in sesame oil. Gold content is approximately 50%. Following IM injection, it is highly protein bound (95%), and peak plasma levels are achieved within 2 to 6 hours. Following a single 50-mg dose, the biological half-life ranges from 3 to 27 days, but following successive weekly doses, the half-life increases to 14 to 40 days after the third dose. The therapeutic effect does not correlate with serum plasma gold levels but appears to depend on total accumulated gold. Aurothioglucose is indicated for the adjunctive treatment of adult and juvenile rheumatoid arthritis.
• Uses: Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice. To produce obesity in experimental animals.
• Clinical Use: Aurothioglucose is highly water soluble, and its aqueous solutions decompose on long standing. It therefore is available as a suspension in sesame oil. Gold content is approximately 50%. Following IM injection, it is highly protein bound (95%), and peak plasma levels are achieved within 2 to 6 hours. Following a single 50-mg dose, the biological half-life ranges from 3 to 27 days, but following successive weekly doses, the half-life increases to 14 to 40 days after the third dose. The therapeutic effect does not correlate with serum plasma gold levels but appears to depend on total accumulated gold. Aurothioglucose is indicated for the adjunctive treatment of adult and juvenile rheumatoid arthritis.